How do estrogen receptors affect bladder ion channels? A new FASEB Journal study reveals ERα and GPER1 regulate Kv7 channels in the rat bladder—with effects that differ by sex and estrous stage.
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#BladderResearch #IonChannels #FASEBJournal

Polyploid superficial uroepithelial bladder barrier cells express features of cellular senescence across the lifespan and are insensitive to senolytics This study characterized umbrella cells, polyploid bladder uroepithelial barrier cells, as an example of potentially beneficial senescent cell present under normal physiology throughout the lifespan ....

Beautiful study from my UConn Center on Aging colleagues showing that
senescence of bladder uroepithelial cells plays a role in normal physiology.
#AgingResearch
#AgingBiology
#BladderResearch
onlinelibrary.wiley.com/doi/10.1111/...