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😯 #TMS #BrainStim

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If you want to present some work, lead a discussion, review a paper, or anything else #TMS at one of our future meetings, then get in touch!

#BrainStim 🧠⚡

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#stats #brainstim #TMS #power 🧠⚡

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This Friday at 14:00 GMT, if you've got nothing better to do, but talk about #TMS #BrainStim theory & methods

👇

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Meetings Resources, data and code to help you run a TMS laboratory - TMSMultiLab/TMSMultiLab

第13屆TMSMultiLab會議將由 @thehandlab.bsky.social主持,會議主題為"Dose-response curves provide a 'ground truth' for testing theories and methods in TMS research"。該會議定於2月27日(星期五)格林尼治標準時間14點。歡迎加入以獲取具體資訊。
github.com/TMSMultiLab/...
#NeuroModulation #TMS #BrainStim @tmsmultilab.bsky.social

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Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN) - PubMed This guideline summarizes updated safety data (2017-2025) and provides expert recommendations on the use of low intensity transcranial electrical stimulation (tES) in humans. tES encompasses several techniques including transcranial direct current stimulation (tDCS), oscillatory transcranial direct …

#recherche | Stimulation électrique transcrânienne de faible intensité : directives en matière de #sécurité, d'#éthique, de #réglementation juridique et d'application

#Ethics #Safety #Training #brainstim #brainstimulation #neuromodulation #stimulationcérébrale
pubmed.ncbi.nlm.nih.gov/41622107/

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The HandLab announces an Exclusive New Episode (#2) of

#TMSIsNotFocal

Foot *and* hand responses from 2cm behind the vertex (~7cm away from hand area)

Blue: thumb muscle
Green: big toe muscle

TMS: Magstim 200^2, 10cm outer diameter figure 8 coil, 2cm behind vertex, 65% MSO

#BrainStim #Methods

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Many thanks to all the authors and 33 other contributors over the past year 🙏 #BrainStim

@solyas.bsky.social @valedichiaro.bsky.social @cassandralowe.bsky.social @pchs0114.bsky.social @phivph.com @fribreuer.bsky.social @neuro-engineer.bsky.social @maggieszymanska.bsky.social @luigitame.bsky.social

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Transcranial magnetic stimulation over supramarginal gyrus stimulates primary motor cortex directly and impairs manual dexterity: implications for TMS focality | Journal of Neurophysiology | American Physiological Society Based on human motor cortex, the effective spatial resolution of transcranial magnetic stimulation (TMS) is often described as 5–20 mm, because small changes in TMS coil position can have large effects on motor-evoked potentials (MEPs). MEPs are often studied at rest, with muscles relaxed. During muscle contraction and movement, corticospinal excitability is higher, thresholds for effective stimulation are lower, and MEPs can be evoked from larger regions of scalp, so the effective spatial resolution of TMS is larger. We found that TMS over the supramarginal gyrus (SMG) impaired manual dexterity in the grooved pegboard task. It also resulted in short-latency MEPs in hand muscles, despite the coil being 55 mm away from the motor cortex hand area (M1). MEPs might be evoked by either a specific corticospinal connection from SMG or a remote but direct electromagnetic stimulation of M1. To distinguish these alternatives, we mapped MEPs across the scalp during rest, isotonic contraction, and manual dexterity tasks and ran electric field simulations to model the expected M1 activation from 27 scalp locations and four coil orientations. We also systematically reviewed studies using TMS during movement. Across five experiments, TMS over SMG reliably evoked MEPs during hand movement. These MEPs were consistent with direct M1 stimulation and substantially decreased corticospinal thresholds during natural movement. Systematic review suggested that 54 published experiments may have suffered from similar motor activation confounds. Our results have implications for the assumed spatial resolution of TMS, and especially when TMS is presented within 55 mm of the motor cortex. NEW & NOTEWORTHY Transcranial magnetic stimulation (TMS) is often described as having an effective spatial resolution of ∼10 mm, because of the limited area of the scalp on which TMS produces motor-evoked potentials (MEPs) in resting muscles. We find that during natural hand movement TMS evokes MEPs from a much larger scalp area, in particular when stimulating over the supramarginal gyrus 55 mm away. Our results show that TMS can be effective at much larger distances than generally assumed.

Just in case you can't believe my heresy, I ran 8 #BrainStim #TMS #NeuroNavigation 🧪 experiments on this topic:

doi.org/10.1152/jn.0...

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A prospective multicentre double-blind randomized controlled trial evaluating clinical, cognitive and neural effects of potentiation of electroconvulsive therapy by repetitive transcranial magnetic stimulation in patients with treatment-resistant depression (STIMAGNECT 2) - PubMed ClinicalTrials.gov NCT06391723 Id RCB: 2023-A01813-42. The trial was registered on January 30, 2024.

#recherche 🔎 | #essaiclinique sur les effets cliniques, cognitifs et neuronaux de la potentialisation des #ECT par la #rTMS chez des patient.e.s atteint.e.s de #DépressionRésistante au traitement (STIMAGNECT 2)

#trials #brainstim #brainstimulation
pubmed.ncbi.nlm.nih.gov/41582128/#fu...

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Meetings Resources, data and code to help you run a TMS laboratory - TMSMultiLab/TMSMultiLab

第12屆TMSMultiLab會議將由Dr Giacomo Bertazzol(orcid.org/0000-0003-1624-2576)主..."The NIBS-BIDS proposal"。該會議定於1月30日(星期五)格林尼治標準時間14點,透過Zoom平台舉行。會議連結將透過Github/Slack發佈,歡迎加入以獲取具體資訊。
github.com/TMSMultiLab/...
#DataSharing #OpenScience #Standards #TMS #BrainStim @tmsmultilab.bsky.social

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Meetings Resources, data and code to help you run a TMS laboratory - TMSMultiLab/TMSMultiLab

The 12th TMSMultiLab meeting will be lead by

Dr Giacomo Bertazzoli
(orcid.org/0000-0003-16...)

on

"The NIBS-BIDS proposal"

Friday 30th Jan, 14h GMT, Zoom

All acronyms will be explained, but its about:

#DataSharing #OpenScience #Standards #TMS #BrainStim

github.com/TMSMultiLab/...

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A cloud of 7,641 datapoints extracted from 354 papers using TMS, showing the mean (x-axis) and SD (y-axis) of the dependent variable (motor evoked potential amplitude). The dots are colour-coded according to whether I flagged the study for containing any obvious biases in methods and/or analyses. Grey shows for data with no obvious bias; blue with some bias - either minor or fixable; red for strong bias - things like removing datapoints post-hoc, restricting variability, major disagreements between values in the text and the figures, or incorrect calculation of SD/SE. The three coloured clouds are largely overlapping, but they occupy different spaces in this graph, with very different linear regression lines. Satisfying to know that subjectively-rated bias has objective, measurable effects on the data.

A cloud of 7,641 datapoints extracted from 354 papers using TMS, showing the mean (x-axis) and SD (y-axis) of the dependent variable (motor evoked potential amplitude). The dots are colour-coded according to whether I flagged the study for containing any obvious biases in methods and/or analyses. Grey shows for data with no obvious bias; blue with some bias - either minor or fixable; red for strong bias - things like removing datapoints post-hoc, restricting variability, major disagreements between values in the text and the figures, or incorrect calculation of SD/SE. The three coloured clouds are largely overlapping, but they occupy different spaces in this graph, with very different linear regression lines. Satisfying to know that subjectively-rated bias has objective, measurable effects on the data.

sneak preview of the #TMS #MetaAnalysis I've been working on for two years...

this isn't the main result, but it's one of the prettiest graphs I've made in some time, so it's worth bragging about.

there's a *lot* going on in this graph - to be explained in a (near?) future thread..!

#BrainStim

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It's our 11th Meeting, and the last of 2025.

Anyone can join, but it probably helps if you like #BrainStim, #NeuroSkyence #Neuroscience #TMS

See you there!

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Report Approval for Transcranial Electrical Stimulation (RATES): expert recommendation based on a Delphi consensus study - PubMed Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however, it suffers from challenges related to reproducibility and quality assessment due to the absence of standardized reporting practices. Here we aim to develop a comprehensive and conse …

#article | Approbation du rapport sur la #stimulationélectrique transcrânienne (RATES) : recommandation d'experts basée sur une #étude consensuelle Delphi

🗞️publié dans la revue #NatureProtocols

#brainstim #brainstimulation #stimulationcérébrale
pubmed.ncbi.nlm.nih.gov/41044265/

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Amazing #TMS #job opportunity alert!

#PostDoc #BrainStim #Parkinsons #Movement 🏴󠁧󠁢󠁷󠁬󠁳󠁿

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Today at 14h GMT, #TMS #BIG #BrainStim

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Our next monthly meeting:

Dr Daniel T Corp will talk about:

Big NIBS data: a repository and pipeline for big data analyses in NIBS

bignibsdata.com

Friday 31st 🎃ctober at 14:00 GMT

Meeting link via Slack & GitHub (link in profile) - join us!

#TMS #BrainStim #NIBS

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Report Approval for Transcranial Electrical Stimulation (RATES): expert recommendation based on a Delphi consensus study - PubMed Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however, it suffers from challenges related to reproducibility and quality assessment due to the absence of standardized reporting practices. Here we aim to develop a comprehensive and conse …

#article: Report Approval for Transcranial Electrical Stimulation (#RATES): expert recommendation based on a Delphi consensus study

pubmed.ncbi.nlm.nih.gov/41044265/
in #NatureProtocols

#NIBS #brainstim

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If you use #TMS, we'd love you to tell us what you do, how you do it, and what you'd like TMSMultiLab to focus on.

Please complete our 5 minute, anonymous survey here:

forms.gle/wjscjzeABAdF...

🙏🙏🙏🙏🙏 #BrainStim #Survey

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We all need to watch out for this - one of the most common errors - in our own & others' work.

It's often described in the paper as:

"Patients with the lowest baseline scores improved the most after the intervention."

⚠️🚩🚨

#RegressionToTheMean #BrainStim

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TMSMultiLab survey TMSMultiLab is a community of ~70 researchers using transcranial magnetic stimulation (TMS). We aim to share methods code and data, to reach consensus & encourage best practice in TMS research methods...

To find out about how #TMS #BrainStim users collect, analyse & share their data, we've made a very brief TMS survey:

forms.gle/83Abpj5F8qzd...

It should take you less than 5 minutes & does not ask for any personal information.

We'll use the answers to plan our future work.

Please share!

🙏🙏🙏

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Transcranial direct current stimulation and online cognitive training to enhance cognitive function and emotional stability in borderline personality disorder: an open-labelled pilot study - PubMed This combined approach appears to be well tolerated and produced promising short-term improvements in cognitive performance, BPD symptoms, and overall functioning. The results underscore the relevance...

#article ! Transcranial direct current stimulation and online cognitive training to enhance cognitive function and emotional stability in #Borderlinepersonality disorder: an open-labelled pilot study

in #jpsychiatryneurosci

#tDCS #brainstim #Borderline
pubmed.ncbi.nlm.nih.gov/40858334/

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Frontiers | Optimising transcranial direct current stimulation application for the enhancement of exercise performance: a review Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that has shown potential in enhancing performance across a range...

✍️Lewis, A., Rattray, B., & Flood, A. (2025). Optimising transcranial direct current stimulation application for the enhancement of exercise performance: a review. Frontiers in Physiology, 16, 1672603. buff.ly/AfWEjaL

#AcademicSky #BrainStimulation #BrainStim #tdcs

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🔔#PublicationAlert🔔 Former #ActiveBrainUC student Aidan, has published a review investigating #TranscranialDirectCurrentStimulation in an exercise context. Check it out here: buff.ly/b0NF20p

#AcademicSky #BrainStimulation #BrainStim #tdcs

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Starting in 6 hours...

Meeting links via github or Slack

#TMS #BrainStim

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Next Generation EEG System Preview
Next Generation EEG System Preview YouTube video by Magstim EGI

@magstimegi.bsky.social #EGI is excited to preview a transformative new #EEG platform: the #Geodesic EEG System (GES) 500:
youtu.be/Pmbf3NmXtC4?...

Sign up for more details here: tinyurl.com/EGI-GES-500
#neuroskyence #Psychology #Neuroscience #TMS #brainstim #Magstim #biomarker #precisionmedicine

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Home Resources, data and code to help you run a TMS laboratory - TMSMultiLab/TMSMultiLab

The #TMSat40 reminiscimeeting is over.

There is much work to do.

If you want to join the effort, see @tmsmultilab.bsky.social and:

github.com/TMSMultiLab/...

#BrainStim #OpenScience

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The *final* stage of the TMS-RAT 🐀 v1.0 is happening... data are being compiled. 😬...

#TMS #BrainStim #SystematicReview

tms-rat.org

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Exciting new work from @phivph.com open your eyes wide 👀 and read! 👇

#TMS #BrainStim

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