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Inside GenPipes: Exploring C3G's Software Solution for Life Science Research - Canadian Centre for Computational Genomics Take a closer look at one of C3G’s software solutions; its purpose, its strengths, its newest features, and how it continues to support the life science community.

From #C3G, the Canadian Centre for Computational Genomics | Inside #GenPipes : Exploring C3G's Software Solution for Life Science Research | #CoreFacility #OpenScience #Genomics #Bioinformatics #Education 🧬 🖥️ 🧪
⬇️
computationalgenomics.ca/inside-genpi...

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Sobi's Aspaveli® Secures European Commission Approval for C3G Treatment Sobi has announced the European Commission's approval of Aspaveli® for treating C3 glomerulopathy in patients aged 12 and above. This marks a major milestone in addressing rare kidney diseases.

Sobi's Aspaveli® Secures European Commission Approval for C3G Treatment #Sweden #Stockholm #Sobi #Aspaveli #C3G

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Iptacopan Is Safe and Effective for Patients With C3G | Docwire News Iptacopan showed strong proteinuria reduction in C3 glomerulopathy (C3G) at 6 months when added to supportive care including RAAS inhibition and immunosuppression.

The phase 3 APPEAR-C3G study showed iptacopan significantly reduced proteinuria at 6 months in people with C3 glomerulopathy. #nephrology #nephsky #C3G
www.docwirenews.com/post/iptacop...

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Early diagnosis matters in C3 glomerulopathy. This #CME activity explores symptom recognition, complement pathways, and emerging therapies.

👉 Watch now: bit.ly/48TbwXO

#MedicalEducation #Nephrology #KidneyDisease #RareDisease #C3G #GlomerularDisease

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Sobi's Aspaveli® Advances Towards Approval for Rare Kidney Diseases in Europe Sobi's Aspaveli® (pegcetacoplan) has gained a positive opinion from the CHMP for treating C3G and IC-MPGN in Europe, a breakthrough for patients.

Sobi's Aspaveli® Advances Towards Approval for Rare Kidney Diseases in Europe #Sweden #Stockholm #Aspaveli #C3G #IC-MPGN

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Trial of Pegcetacoplan in C3 Glomerulopathy and Immune-Complex MPGN | NEJM C3 glomerulopathy and primary immune-complex membranoproliferative glomerulonephritis (MPGN) generally result in glomerular C3 deposition and irreversible kidney damage. The efficacy and safety of ...

Proud of Manchester’s paediatric participation in this game-changing trial published this week in @nejm.org
A golden dawn in renal rare disease
#C3G #IC-MPGN #pegcetacoplan #complement

www.nejm.org/doi/full/10....

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52-Week Data Show Sustained Benefits of Pegcetacoplan in C3G | Docwire News Dr. Carla Nester discussed VALIANT 52-week data presented at ASN Kidney Week 2025 showing sustained proteinuria reduction with pegcetacoplan in complement 3 glomerulopathy (C3G).

Dr. Carla Nester discussed 52-week data on pegcetacoplan for #C3G demonstrating sustained proteinuria reduction (and remission in a third of patients). #nephrology #nephsky #glomerulardisease #kidneywk www.docwirenews.com/post/52-week...

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Trial of Pegcetacoplan in C3 Glomerulopathy and Immune-Complex MPGN | NEJM C3 glomerulopathy and primary immune-complex membranoproliferative glomerulonephritis (MPGN) generally result in glomerular C3 deposition and irreversible kidney damage. The efficacy and safety of ...

Very pleased to see this RCT of Pegcetacoplan in #C3G and primary #ICMPGN published because it shows evidence of a transformational effect of this treatment in people with a #RareDisease. www.nejm.org/doi/full/10....

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Positive Outcomes from VALIANT Phase 3 Study Published in NEJM Highlight Pegcetacoplan's Efficacy for Kidney Diseases The VALIANT Phase 3 study reveals pegcetacoplan's effectiveness for C3 glomerulopathy and primary IC-MPGN, showcasing meaningful clinical benefits.

Positive Outcomes from VALIANT Phase 3 Study Published in NEJM Highlight Pegcetacoplan's Efficacy for Kidney Diseases #Sweden #Stockholm #C3G #pegcetacoplan #IC-MPGN

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#Delphi Consensus on Surrogate Endpoints in #C3G and Primary #ICMPGN

#VisualAbstract by Jade Teakell, MD

www.kireports.org/article/S2468-0249(25)00...

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Join us today for two exciting sessions: our symposium ‘Decoding complement in C3G and primary IC-MPGN’ (🕙13.05 EEST,📍MC3), and Dr Licht’s oral presentation on adolescents with #C3G and primary #IC-MPGN.
Proud to contribute to the scientific dialogue that supports patient care🤝
#Nephrology

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It was a pleasure attending today’s sessions and hearing insightful discussions on #C3G and #IC-MPGN💡

Tomorrow, join us for our lunchtime symposium ‘Decoding complement in C3G and primary IC-MPGN’, followed by an oral presentation focused on adolescents with these rare diseases.
#Sobi_nephrology

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Ready for an exciting day at #ESPN2025. Today Dr Van de Kar will share the first of our two oral presentations on adolescent #C3G and primary #ICMPGN—part of our commitment to advancing understanding of rare #kidney_disease. #Rare_Sobi #Sobi_nephrology
🗓️Thursday 16 October
🕙17.22 EEST
📍TriantiHall

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SEISMIC Film 1 - Strong foundation for critical actions to improve outcomes in C3G and IC-MPGN
SEISMIC Film 1 - Strong foundation for critical actions to improve outcomes in C3G and IC-MPGN YouTube video by CompCure

Today on C3G Awareness Day, we spotlight our SEISMIC initiative where ISGD, NephCure, and CompCure convened leading experts at the SEISMIC summit to advance C3G diagnosis and treatment. Watch the highlights:
youtu.be/GJvgbtMT3xA

youtu.be/Un02dFXyn-w

#C3GAwarenessDay #C3G #ISGD #NephCure #CompCure

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On this #C3GAwarenessDay, check out:
📺 Hot Topics in GN Online Symposium with the Indian Society of Nephrology: www.youtube.com/live/E0PnEj8...
🔊 Latest GN in 10 Podcast w/Carla Nester, focusing on C3G and complement-mediated diseases: www.is-gd.org/podcast

#C3G #GlomerularDisease #ISGD

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Dark Teal background with white circle in middle with yellow border. In the circle it says C3G Awareness Day. Under the circle there is a hashtag #C3GAwarenessDay, and the text Every rare kidney disease deserves to be seen.

Dark Teal background with white circle in middle with yellow border. In the circle it says C3G Awareness Day. Under the circle there is a hashtag #C3GAwarenessDay, and the text Every rare kidney disease deserves to be seen.

Today is #C3GAwarenessDay! At ISGD, we stand with people living with this rare kidney disease. As a medical society for #GlomerularDisease experts, we're committed to raising awareness and moving the science forward to bring more hope and solutions to the C3G community. #C3G #ISGD

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Don’t miss: 'C3G & Immune Complex MPGN Updates: Where We Are & Where We Are Headed’ -Oct 3, 25, all virtual program- latest strategies and therapeutic options. 5.0 ACCME Credits.

www.eventleaf.com/e/C3G2025
#C3G #NephPearls #RareDisease #Nephrology

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An Exciting Future for C3G/IC-MPGN Treatment (Roundtable) | Docwire News Roundtable panelists share their excitement about the future of therapies for glomerulonephritis, including complement 3 glomerulopathy (C3G) and IC-MPGN.

In the final segment of our roundtable, the panelists share their excitement about recent developments in #nephrology and their visions for the future of #glomerulonephritis therapies. #nephsky #c3g #icmpgn www.docwirenews.com/post/an-exci...

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Practical Issues With Implementation of New C3G Therapies (Roundtable) | Docwire News A panel discusses implementing iptacopan and pegcetacoplan to treat complement 3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN).

In the fourth part of our roundtable, the panel delves into the logistics of implementing the new treatments for C3G and IC-MPGN, including safety, vaccination, and adherence. #nephsky #nephrology #c3g #icmpgn www.docwirenews.com/post/practic...

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Kidney Biopsies in Trial Design (Roundtable) | Docwire News A panel discusses the role of kidney biopsies in the clinical trials of two recently approved treatments for complement 3 glomerulopathy (C3G), iptacopan and pegcetacoplan.

In the third part of our recent roundtable, the panel discusses the role of kidney biopsies in the clinical trials of the recently approved treatments for C3G, iptacopan and pegcetacoplan. #nephsky #nephrology #c3g #kidneybiopsy www.docwirenews.com/post/kidney-...

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New Therapeutic Options for C3G and IC-MPGN (Roundtable) | Docwire News A panel discusses approved drugs iptacopan for complement 3 glomerulopathy (C3G) and pegcetacoplan for C3G and immune complex membranoproliferative glomerulonephritis (IC-MPGN).

In part 2 of our inaugural roundtable, the panel discusses two recently approved treatments, iptacopan for C3G and pegcetacoplan for C3G and IC-MPGN. #nephrology #nephsky #c3g #icmpgn #glomerulonephritis www.docwirenews.com/post/new-the...

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Inside:
- KDIGO & ERA sign new MoU

- #APOL1 Conference Report in @kidneyint.bsky.social

- Take the KDIGO Guideline Survey: kdigo.co/Global-Guide...

- KDIGO at SLANH & ANZSN

- New patient resources incl. a #C3G #ICMPGN program with @medliveofficial.bsky.social , @nordrare.bsky.social & NephCure

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Wow! Second approved drug for an ultrarare disease in a few months, and with broader indication. What a milestone!

Time for EMA’s approval now.

#raredisease #glomerulardisease #c3g #nephSky

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FDA Approves Pegcetacoplan for C3G and IC-MPGN | Docwire News The FDA approved pegcetacoplan for treating C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN in patients age 12 and older.

⚠️ The FDA has approved pegcetacoplan (Empaveli) for treating C3G and IC-MPGN. #kidneydisease #nephrology #nephsky #c3g www.docwirenews.com/post/fda-app...

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Living with a #rarekidneydisease often means navigating a maze of late diagnoses, scarce treatment options, and daily symptom management. When #dialysis enters the picture, it can feel like one more heavy layer on an already complex journey.

More at www.rare360.life/post/managin...

#c3g #MPGN

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🌋The SEISMIC meeting has ignited at our kickoff dinner. Tomorrow we will begin discussions on important issues in the shifting C3G and IC-MPGN landscape.
#GlomerularDisease #C3G #ICMPGN #SEISMIC

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Pegcetacoplan Shows Positive Results for Adolescents With C3G and IC-MPGN | Docwire News Pegcetacoplan was found to reduce proteinuria and stabilize eGFR in adolescent patients with C3 glomerulopathy or primary immune complex membranoproliferative glomerulonephritis.

Pegcetacoplan reduced proteinuria and stabilized eGFR in adolescent patients with C3G or primary IC-MPGN. #kidneydisease #c3g #icmpgn #pediatrics #nephrology #nephsky #pegcetacoplan www.docwirenews.com/post/pegceta...

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Pegcetacoplan Benefits Patients With C3G/IC-MPGN and Nephrotic Proteinuria | Docwire News An analysis confirmed the efficacy and safety of pegcetacoplan for patients with C3 glomerulopathy and primary immune complex membranoproliferative and nephrotic range proteinuria.

An analysis confirmed the efficacy and safety of #pegcetacoplan for patients with C3G/IC-MPGN and nephrotic range #proteinuria. #C3G #ICMPGN #kidneydisease #nephrology #nephsky www.docwirenews.com/post/pegceta...

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📣Excited to share with the #nephrology community the latest updates in #C3G and primary #ICMPGN clinical trials at #ERA25. If you are a healthcare professional, do not miss the late breaking session: Innovative Kidney Trials at ⏲️15:00 at the Square #nephrology #kidneydisease

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