Brilliant work by Xinpei Jiang, the first PhD student of the #CañadasLab! #proud

Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer Spliceosome inhibitors emerged as promising anticancer agents. Recent studies have demonstrated that spliceosome-targeted therapies (STTs) trigger ant…

Super excited that our paper is out in Cell Reports @cp-cellreports.bsky.social! We show that spliceosome inhibitors trigger ZBP1-driven necroptosis in small cell lung cancer #SCLC enhancing immunotherapy responses! #CañadasLab! #FoxChaseCancer www.sciencedirect.com/science/arti...