Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer Spliceosome inhibitors emerged as promising anticancer agents. Recent studies have demonstrated that spliceosome-targeted therapies (STTs) trigger ant…

Super excited that our paper is out in Cell Reports @cp-cellreports.bsky.social! We show that spliceosome inhibitors trigger ZBP1-driven necroptosis in small cell lung cancer #SCLC enhancing immunotherapy responses! #CañadasLab! #FoxChaseCancer www.sciencedirect.com/science/arti...

Don’t miss this poster (section 2 board 9) today by my friend & colleague Janusz Franco-Barraza from #FoxChaseCancer about the #TME of a unique #Hodgkin #Lymphoma case (using multiplex sequential IF)

#AACR25 #AACR2025 @theaacr.bsky.social

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#AACR25

A Bioprinted Sea-and-Island Multicellular Model for Dissecting Human Pancreatic Tumor-Stroma Reciprocity and Adaptive Metabolism Pancreatic ductal adenocarcinoma (PDAC) presents a formidable clinical challenge due to its intricate microenvironment characterized by desmoplasia an…

Bioprinted Sea-&-Island Multicellular Human #PancreaticCancer Model; tumor/stroma signal reciprocity
By #JanuszFranco & #binhamton NY colleagues.
#CukiermanLab #FCCCGreenberg #FoxChaseCancer #templemedschool www.sciencedirect.com/science/arti...