#CancerAssociatedFibroblasts -derived fibronectin EDA drives #Sorafenib resistance in #HCC via SHMT1 activation, highlighting a novel fibroblast-tumor interaction that governs therapeutic response in #LiverCancer.
#OpenAccess: doi.org/10.1016/j.ge...
NOX4/NOX1 dual inhibition in #CancerAssociatedFibroblasts impairs the pro-tumorigenic effects of TGF-β signalling functions and reduces tumour growth in intrahepatic cholangiocarcinoma (iCCA).
#STTT #OpenAccess: doi.org/10.1038/s413...
They cultured our immortalized CAFs with Renca cells before implanting them in mice to study the immunotherapy. Our selection of CAFs enable all sort of tumor models, including 3D in vitro models and in vivo models.
#kidneycancer #cancerassociatedfibroblasts
📌 OncoTerm - Word of the Day! 👋
📌 OncoTerm - Günün Kelimesi! 👋
Join us as we break down key terms to empower ourselves with knowledge in the fight against cancer.
#Onco404 #Cancer #Kanser #CancerAwareness #CancerAssociatedFibroblasts #CAF #TumorMicroenvironment #TME #MedSky #OncSky #Vocabulary