🗣️New study showing the correlation of #CirculatingCalprotectin and disease activity in PsA.

''Evaluation of Serum Calprotectin Levels and Their Relationship with Disease Activity in Psoriatic Arthritis and Axial Spondyloarthritis''

#Rheumatology #RheumSky #PsA

www.mdpi.com/1648-9144/62...

Prognostic significance of serum Mrp 8/14 in acute respiratory distress syndrome induced by pulmonary and extrapulmonary sepsis: A retrospective controlled study To date, it remains unclear whether serum Mrp 8/14 is differentially expressed in sepsis-induced ARDS patients of pulmonary and extrapulmonary origin during ICU hospitalization. This study investigate...

#CirculatingCalprotectin levels upon ICU admission as prognostic indicator for predicting the mortality in patients with sepsis-induced pulmonary ARDS during ICU hospitalization.

www.resmedjournal.com/article/S095...

Neutrophil activation in juvenile dermatomyositis: associations with muscle function and disease progression - Pediatric Rheumatology Background Juvenile dermatomyositis (JDM) is an inflammatory vasculopathy characterized by muscle weakness and systemic inflammation. This study aimed to investigate the clinical utility of neutrophil...

Neutrophil activation in juvenile dermatomyositis: associations with muscle function and disease progression

#CirculatingCalprotectin and MPO-DNA as potential biomarkers for JDM muscle inflammation and functional outcomes.

#RheumSky

ped-rheum.biomedcentral.com/articles/10....

Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein Objectives C reactive protein (CRP) is frequently normal in psoriatic arthritis (PsA) despite active disease, complicating inflammation assessment. This study aimed to evaluate alternative biomarkers ...

👉Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein

#RheumSky #CirculatingCalprotectin

rmdopen.bmj.com/content/11/3...

Circulating calprotectin - the power to assess inflammation 2/2025 As we move into the second half of 2025, we are pleased to provide an update on GCAL® - our assay for circulating calprotectin - and to highlight recent research and studies that continue to expand kn...

Happy to share the newest Gentian GCAL newsletter. Tune in for updates and insights. #CirculatingCalprotectin #RheumSky

www.linkedin.com/pulse/circul...

Frontiers | The role of calprotectin in giant cell arteritis - from pathophysiology to possible clinical applications Giant cell arteritis (GCA) is an immune-mediated vasculitis predominantly affecting individuals aged 50 years and older, with clinical manifestations often o...

Fresh off the press, this review takes a deep look into #CirculatingCalprotectin in GCA.

www.frontiersin.org/journals/imm...

#RheumSky

How serum calprotectin is transforming rheumatic disease diagnosis Discover how serum calprotectin is advancing the diagnosis, monitoring, and treatment of rheumatic diseases. Learn about its role in predicting flare-ups and guiding personalized care.

👏 SelectScience editorial on #CirculatingCalprotectin received an award for the best ''Clinical Diagnostics Editorial Article of the Year'' at #ADLM this year.

#RheumSky

www.selectscience.net/article/how-...

Frontiers | Assessment of S100A8/A9 and resistin as predictive biomarkers for mortality in critically ill patients with sepsis IntroductionSepsis is associated with high mortality. Early intervention is crucial to reducing sepsis-related mortality. This study aims to assess the clini...

''Serum S100A8/A9 concentration at ICU admission is a significant predictor of 28-day mortality risk in sepsis patients''

#CirculatingCalprotectin #Sepsis

www.frontiersin.org/journals/cel...

Biomarkers in juvenile idiopathic arthritis: towards... : Current Opinion in Rheumatology years, research has increasingly focused on the identification and validation of biomarkers to enhance diagnostic precision, predict disease course, and guide therapeutic decisions. Recent findings ...

Review: Biomarkers in juvenile idiopathic arthritis: towards precision diagnosis and personalized therapy?

#CirculatingCalprotectin as promising tool for monitoring and prognosis in JIA by its ability to predict flares and subclinical inflammation.

#RheumSky

journals.lww.com/co-rheumatol...

Plasma proteomics identifies S100A8/A9 as a novel biomarker and therapeutic target for fulminant myocarditis Fulminant myocarditis (FM) is a lethal inflammatory myocardial disease characterized by rapid progression and poor prognosis. Investigating plasma pro…

🗣️ #CirculatingCalprotectin identified as a crucial biomarker and potential therapeutic target of fulminant myocarditis.

High levels associated with longer hospital stays and higher risks of adverse outcomes.

#CardioSky

www.sciencedirect.com/science/arti...

Diagnosis, management, and monitoring of interleukin-1 mediated diseases in Central and Eastern Europe: real-world data - Pediatric Rheumatology Background Global healthcare disparities, stemming from organizational differences in healthcare systems, lead to variable availability and funding, resulting in a gap between recommended and implemen...

🧐 #CirculatingCalprotectin availability is increasing in several European countries.

According to the 2021 EULAR/ACR recommendations, the clinical examination of systemic inflammation for IL-1 diseases should now also include calprotectin if accessible.

ped-rheum.biomedcentral.com/articles/10....

Association of Elevated Serum S100A8/A9 Levels and Cognitive Impairment in Systemic Lupus Erythematosus Patients Objectives Cognitive impairment (CI) is common in patients with Systemic Lupus Erythematosus (SLE). Despite its prevalence, the immune mechanisms are not well understood. We previously reported elev...

🧠 New study in #SLE patients links elevated #CirculatingCalprotectin to cognitive impairment. Higher levels correlated with worse performance across domains—and tracked with changes in cognitive status over 1 year.

#RheumSky

acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

Calprotectin and Atherosclerotic Cardiovascular Disease This population-based cohort study examines the prospective association between circulating calprotectin and atherosclerotic cardiovascular disease as well as the mechanistic contributions of calprote...

🤔New #CirculatingCalprotectin Publication: ''Calprotectin has the potential to be a mechanistically informed biomarker for ASCVD, independent of traditional and contemporary cardiovascular risk factors and biomarkers.''

jamanetwork.com/journals/jam...

#RheumSky #Calprotectin

Evaluation of serum calprotectin levels in patients with polycystic ovary syndrome - Scientific Reports Scientific Reports - Evaluation of serum calprotectin levels in patients with polycystic ovary syndrome

🧐 #CirculatingCalprotectin in Polycystic ovary syndrome reported to provide insights into the inflammatory processes.

www.nature.com/articles/s41...

#StillsDisease diagnosis is often delayed.
#CirculatingCalprotectin can be an important part in early differentiation from infections and other inflammatory causes of presented symptoms. (Recommended by PReS/EULAR guidelines.)

#RheumaSky #EULAR #PReS

Circulating calprotectin - the power to assess inflammation 1/2025 We are excited to welcome you to the first newsletter of 2025! As we look back on a transformative 2024, it’s clear that the awareness of the clinical impact of circulating calprotectin continues to g...

Happy to share the first Gentian GCAL newsletter of 2025. Tune in for updates and insights. #CirculatingCalprotectin

www.linkedin.com/pulse/circul...

Highlights from the breakout session: vasculitis in paediatric rheumatology Abstract. The 21st International Vasculitis Workshop, held in Barcelona, Spain, from April 7 to 10, 2024, highlighted advances in pediatric vasculitis, foc

Highlights from Breakout session in vasculitis in paediatric rheumatology. Including results of #Calprotectin (S100A8/A9) in IgA vasculitis, where elevated levels were significantly associated with active disease.

academic.oup.com/rheumatology...

#ReuhmaSky #CirculatingCalprotectin

Prognostic value of serum Mrp 8/14 in sepsis-induced acute respiratory distress syndrome patients: a retrospective cohort study Background Mrp 8/14 is abundantly secreted by activated neutrophils during infection and inflammation. However, its prognostic value in acute respiratory distress dyndrome (ARDS) induced by sepsis is ...

#CirculatingCalprotectin predicting mortality in sepsis-induced ARDS patients during ICU hospitalization

''Prognostic value of serum Mrp 8/14 in sepsis-induced acute respiratory distress syndrome patients: a retrospective cohort study''
peerj.com/articles/187...

#ICU #sepsis #biomarker #S100A8/A9

Circulating calprotectin in rheumatic diseases Calprotectin in serum and plasma has been described as valuable biomarker in several chronic inflammatory conditions, including multiple rheumatic conditions

𝗨𝗻𝗹𝗼𝗰𝗸𝗶𝗻𝗴 𝗶𝗻𝘀𝗶𝗴𝗵𝘁𝘀 𝗶𝗻𝘁𝗼 #𝗥𝗵𝗲𝘂𝗺𝗮𝘁𝗶𝗰𝗗𝗶𝘀𝗲𝗮𝘀𝗲𝘀 𝘄𝗶𝘁𝗵 #CirculatingCalprotectin 𝘁𝗲𝘀𝘁𝗶𝗻𝗴, 𝗮𝘀 𝘁𝗵𝗶𝘀 𝗯𝗶𝗼𝗺𝗮𝗿𝗸𝗲𝗿 𝘁𝗿𝗮𝗻𝘀𝗳𝗼𝗿𝗺𝘀 𝘁𝗵𝗲 𝗹𝗮𝗻𝗱𝘀𝗰𝗮𝗽𝗲 𝗼𝗳 𝗿𝗵𝗲𝘂𝗺𝗮𝘁𝗶𝗰 𝗱𝗶𝘀𝗲𝗮𝘀𝗲 𝗺𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁.

www.gentian.com/news/circula...

#RheumSky

KL‑6, ET‑1 and S100A9 levels in patients with idiopathic pulmonary fibrosis and obstructive sleep apnea Obstructive sleep apnea (OSA) and idiopathic pulmonary fibrosis (IPF) frequently coexist. Elevated levels of Krebs von den Lungen-6 (KL-6), endothelin-1 (ET-1) and S100 calcium-binding protein A9 (S10...

#CirculatingCalprotectin
as one potential biomarker in OSA signature.

KL‑6, ET‑1 and S100A9 levels in patients with idiopathic pulmonary fibrosis and obstructive sleep apnea

pmc.ncbi.nlm.nih.gov/articles/PMC...

Inflammatory biomarker analysis confirms reduced disease severity in heterozygous patients with familial Mediterranean fever Introduction Familial Mediterranean fever (FMF) is a genetic disease leading to recurrent episodes of inflammation. Two pathogenic variants are required for classical disease, but the disease can occu...

🧐 #CirculatingCalprotectin in FMF: S100 proteins are key biomarkers to differentiate patients with class IV-V variants from those with class III variants

rmdopen.bmj.com/content/10/4...

Serum S100A8/A9 Correlates to Surgery‐Free Interval in Idiopathic Subglottic Stenosis This study investigates the potential of S100A8/A9 as a prognostic biomarker in Idiopathic Subglottic Stenosis (iSGS), a condition predominantly affecting women of northern European descent. Serum S1...

🤔 #CirculatingCalprotectin as a progonostic marker in Idiopathic Subglottic Stenosis
onlinelibrary.wiley.com/doi/10.1002/...

FAQ: What role has circulating calprotectin in vasculitis? The use of serum or plasma calprotectin as inflammation and activity biomarker in different forms of vasculitis

From our FAQ series for
#CirculatingCalprotectin

www.gentian.com/news/circula...

FAQ: What is the value of circulating calprotectin in JIA & Still’s disease? The neutrophilic protein calprotectin has been described as valuable biomarker in several rheumatic conditions, including rheumatoid arthritis (RA) and JIA

From our FAQ series for #CirculatingCalprotectin

www.gentian.com/news/plasma-...

Circulating calprotectin - the power to assess inflammation 3/2024 We are witnessing a growing global demand for circulating calprotectin, underscoring its recognition as a valuable biomarker in detection and assessment of inflammation and inflammatory response to in...

Excited to share our newsletter covering the latest news, developments, and updates in #CirculatingCalprotectin
Circulating calprotectin - the power to assess inflammation 3/2024 linkedin.com/pulse/circul...