G/C-ending and synonymous codon bias define functional translational programs that shape human tissue and cancer proteomes Abstract. Codon usage bias is a fundamental feature of the genetic code, yet its impact on messenger RNA translation is incompletely defined. Here, we inte

Excited to share our new paper in NAR Genomics and Bioinformatics (Editor’s Choice).
We show that Synonymous codons are not as interchangeable as they seem and that codon bias helps define functional translational programs in humans.

#codonbias #translation #tRNA #cancerbiology

📝 Online now - the Review "Mapping rRNA, tRNA, and mRNA modifications in ribosomes at high resolution" from Lukasz Koziej and Sebastian Glatt.

#RNAmodifications #epitranscriptomics #TranslationRegulation #CodonBias #TherapeuticTargeting

Read it here: authors.elsevier.com/a/1lnYa3S6Gf...