Amphotericin B has activity against most species. Aggressive therapy for disseminated infection. Other antifungals with good coverage against most #Curvularia species include Voriconazole, Itraconazole, and Posaconazole.

714. Invasive Fungal Infection Caused by Curvularia Species in a Patient with Intranasal Drug Use: A Case Report AbstractBackground. Invasive fungal infections (IFIs) are uncommon infections that account for approximately 27.2/100,000 cases per year in the United Stat

intranasal cocaine resulting in #curvularia invasive infection academic.oup.com/ofid/article...

613. The Clinical Spectrum of Curvularia Species: A 20-year Experience at 2 Tertiary Care Hospitals AbstractBackground. Curvularia species are dematiaceous environmental molds that rarely cause disease in humans. Infections may be superficial or invasive

#curvularia academic.oup.com/ofid/article...

#Curvularia distinguished from Bipolaris & Drechslera by its conidial septa lying from one side wall to other (not distoseptate). Also, unlike Bipolaris, conidium of Curvularia is usually curved, has enlarged, darker central cell, thinner cell wall & narrower septations b/w cells

#Curvularia is a dematiaceous fungus found ubiquitously in soil. Curvularia & other dematiaceous fungi are seen in tissue sections as 2- to 6-μm-wide hyphal forms which differ greatly in length and may be fragmented. Vesicular swellings of hyphae producing bizarre hyphal outlines

https://doi.org/10.1093/ofid/ofab536

#Curvularia endocarditis/mycotic aneurysm: rare only few cases 1) aortic root involvement,2) occurring within 6 mo post aortic valve replacement, 3) didnt originate from cutaneous or sinopulmonary source, 4)immunocompetent host Ref t.co/wZ1EA19tPE

Five novel species of Curvularia (Pleosporales, Pleosporaceae) isolated from turfgrasses Curvularia, a cosmopolitan fungal genus, occupies various ecological niches, but displays a pronounced tendency to colonise the leaves of plants. In this study, several fungal isolates with similar ch...

Five novel species of Curvularia (Pleosporales, Pleosporaceae) isolated from turfgrasses

#Curvularia
#Pleosporales
#Pleosporaceae
#Fungaldiversity
#Helminthosporioidfungi
#hyphomycetes
#phylogeny
#taxonomy

mycokeys.pensoft.net/article/1686...

#Curvularia distinguished from Bipolaris & Drechslera by its conidial septa lying from one side wall to other (not distoseptate). Also, unlike Bipolaris, conidium of Curvularia is usually curved, has enlarged, darker central cell, thinner cell wall & narrower septations b/w cells

Amphotericin B has activity against most species. Aggressive therapy for disseminated infection. Other antifungals with good coverage against most #Curvularia species include Voriconazole, Itraconazole, and Posaconazole.

#Curvularia is a dematiaceous fungus found ubiquitously in soil. Curvularia & other dematiaceous fungi are seen in tissue sections as 2- to 6-μm-wide hyphal forms which differ greatly in length and may be fragmented. Vesicular swellings of hyphae producing bizarre hyphal outlines #idsky

Cns #curvularia main postulated mechanism of disease is hematogenous spread from a possible subclinical pulmonary focus; direct extension from associated sinus disease is another possibility

In CNS #phaeohyphomycosis most frequent dematiaceous fungi species isolated is Cladophialophora bantiana but occasionally CNS phaeohyphomycosis due to #Curvularia spp. have been reported

Multifocal cerebral #phaeohyphomycosis due to #Curvularia croissant shaped ref pmc.ncbi.nlm.nih.gov/articles/PMC...