Long‑term #EGCG administration prevents #aging‑related cardiac #DiastolicDysfunction and #exercise decline by alleviating #apoptosis, mitochondrial damage, and restoring #CardiacTroponinI, highlighting EGCG as a preventive strategy for #HFpEF.

#OpenAccess: doi.org/10.1016/j.ge...

In restrictive #cardiomyopathy mice with cTnI R193H mutation, early #DiastolicDysfunction features prolonged relaxation, enhanced #glycolysis, and PI3K/AKT‑driven #glucoseuptake, linking altered energy metabolism to #fibrosis and #HeartFailure.

#OpenAccess: doi.org/10.1016/j.ge...

This study explores the energy status & regulation of #Glucose & #FattyAcid utilization in cTnI193His-M mice in the early stages of #DiastolicDysfunction, providing insights for future #therapeutic strategies for #HeartFailure. #medsky
#OpenAccess:
www.sciencedirect.com/science/arti...