Mary and Alec have back to back talks this morning in West Moscone 2014 in the 11-1 session! Come cheer them on and see all the cool machine learning work they’ve been doing!! #ECPromo2025 #ats2025 @NM_Lung @NUFeinbergMed @NU_IntMed @NorthwesternMed
More work however needs to be done on how we assess frailty in the ICU, the biological underpinnings, and how we can improve outcomes. Hopefully there’ll be more studies in the future for us to hear about at next year’s ATS! (10/10) 🧵 The End
#ECPromo2025 #ats2025 #ATSCritCareLive
Dr. Nathan Brummel cautions against using frailty to decide if critical care should be recommended, as we could be conflating the impact of acute illness with frailty. 🚧 (8/10)
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What can we do about frailty then in the ICU? Here's a guide! 👇 (7/10)
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Not all frailty is the same. There are physical, psychological, and social domains and we need to address the right domain. For the physical domains, there are multiple pathways and fortunately exercise and nutrition benefit most of these pathways! 💪 (6/10)
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Dr. Jon Singer shared some good news- frailty is treatable! Most interventions for frailty focus on exercise +/- nutrition and on a group level, these improve frailty. 🏋️♀️ 🥬 However, exercise and diet require behavior change, which can be challenging. (5/10)
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Dr. Eleanor Kate Phillips discussed that frailty is a state of disrupted homeostasis. In chronic frailty, many genes are overrepresented, especially in immune response. 🦠 (4/10)
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Despite this, in a review of critical care interventions, only one RCT had subgroup data for frailty! Given its impact on outcomes, Dr. Ferrante suggests we add frailty to our pre-specified subgroup analyses to our RCTs. 📊 (3/10)
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Dr. Lauren Ferrante shared data showing that frailty is associated with worse in-hospital and long-term mortality. It’s also associated with worse QOL for patients. (2/10)
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We heard some excellent talks this morning at ATS on frailty, and we’re here to give you some of the key takeaways! A thread 🧵 (1/10)
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More #ecpromo2025 @NM_Lung @NUFeinbergMed @NU_IntMed @NorthwesternMed #ATS2025 at the poster hall right now!!
Vijeeth presenting Poster 305 in B27 Discussion Monday 9:15. @SakiAmagai presenting Poster #901 at C103 Discussion Tuesday 2:15!
@MaryMengouZhu and @alecpeltekian both giving podium presentations on pneumonia machine learning Wednesday 11AM session D96!
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Congrats @MaryMengouZhu @alecpeltekian on abstract awards! Congrats @SakiAmagai Vijeeth on student scholars awards! #ECPromo2025 #ATS2025
