Is Handedness at Five Associated with Prenatal Factors? The goal of the study was to investigate some of the factors suspected to be related to children’s handedness: presentation during the last weeks of gestation and at birth (cephalic or breech), side of presentation (right or left), number of weeks of gestation, season of birth, parents’ handedness and sex. We analyzed the relationships between these factors and the child’s handedness at five years. Children (n = 1897) from the EDEN cohort participated in the study, among which 1129 were tested for handedness at five. The father’s handedness, but not the mother’s, was significantly related to the child’s hand preference. The percentage of left-handed children was significantly larger when the father was non-right-handed compared to right-handed, and tended to be larger among children in non-left-cephalic presentation compared to left-cephalic presentation. Girls, but not boys, were significantly less lateralized when they were born before 37 weeks of pregnancy than after. Finally, children born in winter or spring were slightly but significantly less lateralized than children born in summer or autumn. All six children who were not lateralized at 5 presented one or several of these factors. These results are discussed in light of the mixed model of handedness.

Is child handedness at age 5 years associated with prenatal factors?
Examination of parental #handedness, gestational age, side of presentation at birth, season of birth and child sex in the #EDENcohort

Here:via @MDPIOpenAccess

mdpi.com/1051874

Ravi d'avoir contribué à ce Canal Détox ! ⬇️

Pour rester au courant de toutes nos recherches sur les liens entre usage des écrans 📺📱et santé de l'enfant 🧒🏽, restez branchés... 🙃

#EDENcohort #ELFEcohort #GUSTOcohort
@Inserm @CRESS_U1153

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▶️Want to join the world's second most impactful institution in health research? @Inserm

▶️Want to analyse data from world-leading birth cohorts? #EDENcohort #ELFEcohort #GUSTOcohort

▶️Want to collaborate with outstanding scientists from @NUSingapore @astar_research?

▶️Envie de rejoindre @Inserm et le Centre de recherche en épidémiologie et statistiques @CRESS_U1153 ?

▶️Envie d'analyser les données des études #EDENcohort et #ELFEcohort ? @InedFr

▶️Envie de collaborer avec @FranckRamus, @mkmelchior, et d'autres scientifiques ?

📰Nouvelle publication de l'étude #EDENcohort : fumer pendant mais aussi avant la grossesse entraîne des modifications épigénétiques #methylation de l'ADN du #placenta. 🚬🤰🏻

Lien vers @BMCMedicine ➡️Communiqué de presse @Inserm ⬇️

presse.inserm.fr/le-placenta-co… rdcu.be/b8bNX

[#Recrutement]
Le @CRESS_U1153 @InsermIDF recrute un chef de projet en santé publique ! Coordination et gestion d'études épidémiologiques #EDENcohort et #ECAILtrial.
Fiche de poste :#emploi #paris @Inserm
RT apprécié !

tinyurl.com/y526jyw7

Breast milk n-3 long-chain polyunsaturated fatty acids and blood pressure: an individual participant meta-analysis

📰New paper in Eur J Nutr.
🤱🏻No associations between #breastmilk n-3 #LCPUFA and children's blood pressure were observed among 2,188 mother-child pairs from 7 european cohorts.
#nullresult #EDENcohort @MartineArmand13
➡️

rdcu.be/b47J4

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📣 Le @CRESS_U1153 @Inserm recherche un ou une ingé data manager & stats | Projets européens @LongITools @LifeCycle_EU | #EDENcohort #ELFEcohort #epitwitter
Plus d'info ici :

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OBGYN Postnatal faecal incontinence was associated with depression; postnatal screening should be encouraged and psychological support offered.

New #EDENcohort article just out in @BJOGTweets:

Postpartum psychological distress associated with anal incontinence in the EDEN mother–child cohort.

x.com/DrSherryThomas… doi.org/10.1111/1471-0…

Deriving the Dietary Approaches to Stop Hypertension (DASH) Score in Women from Seven Pregnancy Cohorts from the European ALPHABET Consortium The ALPHABET consortium aims to examine the interplays between maternal diet quality, epigenetics and offspring health in seven pregnancy/birth cohorts from five European countries. We aimed to use the Dietary Approaches to Stop Hypertension (DASH) score to assess diet quality, but different versions have been published. To derive a single DASH score allowing cross-country, cross-cohort and cross-period comparison and limiting data heterogeneity within the ALPHABET consortium, we harmonised food frequency questionnaire (FFQ) data collected before and during pregnancy in ≥26,500 women. Although FFQs differed strongly in length and content, we derived a consortium DASH score composed of eight food components by combining the prescriptive original DASH and the DASH described by Fung et al. Statistical issues tied to the nature of the FFQs led us to re-classify two food groups (grains and dairy products). Most DASH food components exhibited pronounced between-cohort variability, including non-full-fat dairy products (median intake ranging from 0.1 to 2.2 servings/day), sugar-sweetened beverages/sweets/added sugars (0.3–1.7 servings/day), fruits (1.1–3.1 servings/day), and vegetables (1.5–3.6 servings/day). We successfully developed a harmonized DASH score adapted to all cohorts being part of the ALPHABET consortium. This methodological work may benefit other research teams in adapting the DASH to their study’s specificities.

📄New publication in @Nutrients_MDPI: Deriving the DASH Score in Women from Seven Pregnancy Cohorts from the European ALPHABET Consortium, including @CO90s @GenerationR_010 and #EDENcohort. Challenging but we made it. @LingWei_Chen
▶️#mdpinutrients

mdpi.com/2072-6643/11/1…

📃Latest publication by the #EDENcohort and #ELFEcohort teams. Time spent in sedentary behavior during pregnancy associated with increased likelihood of postpartum depression symptoms. @Fabienne_EK

x.com/MaritaHennessy…

📃New #EDENcohort article by @BarbaraHeude and colleagues published in #PediatricObesity. As early as infancy higher energy intake and greater appetite mediate part of the relationship between genetic susceptibility to obesity and childhood BMI. 🍽️Here:

onlinelibrary.wiley.com/doi/abs/10.111…

Nos résultats les plus récents dans #EDENcohort présentés (avec succès) par @Martinearmand7 lors des #JFN2018 #LESJFN à suivre...

x.com/SFNutrition_Fr…

Language and motor skills differences between boys and girls in early childhood: where do they come from❓
Not from the factors examined in our latest #EDENcohort article just published in Journal of Experimental Child Psychology.@FranckRamus

sciencedirect.com/science/articl…

New data from #EDENcohort just published in @IntJObesity. Socioeconomic inequalities in childhood overweight and growth appear in early life. By Ballon, @JeremieBotton et al.

nature.com/articles/s4136…

📄 Latest #EDENcohort paper led by @RemySlama and Johanna Lepeule and published in Environment International. NO2 exposure during #pregnancy associated with #methylation level of ADORA2B, a gene whose expression was previously associated with hypoxia and pre-eclampsia. @Inserm

<em>Journal of Child Psychology and Psychiatry</em> | ACAMH Pediatric Journal | Wiley Online Library Background Evidence shows that diet contributes substantially to lifelong physical and mental health. Although dietary exposure during gestation and early postnatal life is critical, human epidemiol...

Our latest #EDENcohort article published in @TheJCPP: Prenatal diet and children's trajectories of hyperactivity–inattention and conduct problems from 3 to 8 years: the EDEN mother–child cohort

onlinelibrary.wiley.com/doi/10.1111/jc…

Maternal smoking mediates half the effect of education on birth size. #EDENcohort #NandG2018

Our latest contribution to this under-studied scientific topic: maternal diet and breast milk lipid content in #EDENcohort

x.com/AliYarrow/stat… clinicalnutritionjournal.com/article/S0261-…

In-utero exposure to phenols and phthalates and the intelligence quotient of boys at 5 years - Environmental Health Background There are concerns that developmental exposure to endocrine disrupting chemicals such as phenolic compounds and phthalates could affect child cognitive function. Epidemiological studies tackling this question have mainly focused on phthalate metabolites and bisphenol A, but not on the other phenolic compounds. Our study aimed to assess the relationship between in-utero exposure to phthalates, bisphenol A and other phenolic compounds (parabens, triclosan, dichlorophenols and benzophenone-3) and the Intelligence Quotient (IQ) of boys at 5–6 years. Methods In 452 mother-son dyads from the French EDEN cohort, we measured 11 phthalate metabolites and 9 phenolic compounds (4 parabens, benzophenone-3, bisphenol A, 2 dichlorophenols and triclosan) in spot urine samples collected between 22 and 29 gestational weeks. Verbal and performance IQ of children were assessed at 5–6 years by a psychologist using the Wechsler Preschool and Primary Scale of Intelligence (WPPSI). We used adjusted Structural Equation Models (SEM) combined with Benjamini and Hochberg false discovery rate correction to assess the associations between maternal urine phenol and phthalate metabolite concentrations considered simultaneously and the boys’ IQ. Results No phenol or phthalate metabolite concentration was negatively associated with the boys’ verbal or performance IQ (uncorrected p-values ≥0.09). Mono(3-carboxypropyl) phthalate tended to be associated with increased verbal IQ (β = 0.136, 95% confidence interval, 0.01; 0.27). This association disappeared after correction for multiple comparison (corrected p-value, 0.71). Conclusion Our results did not provide evidence of an inverse association between in-utero exposure to phenols or phthalates and verbal and performance IQ among boys. Since phenols and phthalates may have sex-specific effects, these null findings cannot be generalized to girls. Limitations included use of a single spot urine sample to assess exposures and lack of consideration of postnatal exposures.

Our new publication in #EDENcohort:
In-utero exposure to phenols and phthalates and #IQ of boys at 5 years

ehjournal.biomedcentral.com/articles/10.11…