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Graphical abstract illustrating the proposed mechanism by which prenatal OLA exposure disrupts placental vascular development, leading to intrauterine growth restriction (IUGR) in mice. Specifically, OLA released from orally ingested polylactic acid plastics during pregnancy interferes with GATA2-regulated VEGF signaling, thereby impairing placental vascular development. The mechanistic scheme was created using Figdraw.

Graphical abstract illustrating the proposed mechanism by which prenatal OLA exposure disrupts placental vascular development, leading to intrauterine growth restriction (IUGR) in mice. Specifically, OLA released from orally ingested polylactic acid plastics during pregnancy interferes with GATA2-regulated VEGF signaling, thereby impairing placental vascular development. The mechanistic scheme was created using Figdraw.

#PolylacticAcid is a #biodegradable #plastic that can be broken down into oligomeric lactic acid (OLA) #nanoplastics. This study shows that OLA particles can accumulate in mouse #placenta & #fetus, inducing placental vascular dysplasia & fetal growth restriction @plosbiology.org 🧪 plos.io/4bR4e6W

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Placental Steroid Hormones in Preeclampsia: Multilayered Regulation of Endocrine Pathogenesis Abstract. The human placenta serves as the predominant endocrine organ throughout pregnancy, assuming a central role in preserving endocrine homeostasis, f

Placental Steroid Hormones in Preeclampsia: Multilayered Regulation of Endocrine Pathogenesis. Read more in #EndocrineReviews: bit.ly/4usDAtz #placenta #trophoblast #testosterone @endocrinesociety.bsky.social

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Graphical abstract illustrating the proposed mechanism by which prenatal OLA exposure disrupts placental vascular development, leading to intrauterine growth restriction (IUGR) in mice. Specifically, OLA released from orally ingested polylactic acid plastics during pregnancy interferes with GATA2-regulated VEGF signaling, thereby impairing placental vascular development. The mechanistic scheme was created using Figdraw.

Graphical abstract illustrating the proposed mechanism by which prenatal OLA exposure disrupts placental vascular development, leading to intrauterine growth restriction (IUGR) in mice. Specifically, OLA released from orally ingested polylactic acid plastics during pregnancy interferes with GATA2-regulated VEGF signaling, thereby impairing placental vascular development. The mechanistic scheme was created using Figdraw.

#PolylacticAcid is a #biodegradable #plastic that can be broken down into oligomeric lactic acid (OLA) #nanoplastics. This study shows that OLA particles can accumulate in mouse #placenta & #fetus, inducing placental vascular dysplasia & fetal growth restriction @plosbiology.org 🧪 plos.io/4bR4e6W

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Graphical abstract illustrating the proposed mechanism by which prenatal OLA exposure disrupts placental vascular development, leading to intrauterine growth restriction (IUGR) in mice. Specifically, OLA released from orally ingested polylactic acid plastics during pregnancy interferes with GATA2-regulated VEGF signaling, thereby impairing placental vascular development. The mechanistic scheme was created using Figdraw.

Graphical abstract illustrating the proposed mechanism by which prenatal OLA exposure disrupts placental vascular development, leading to intrauterine growth restriction (IUGR) in mice. Specifically, OLA released from orally ingested polylactic acid plastics during pregnancy interferes with GATA2-regulated VEGF signaling, thereby impairing placental vascular development. The mechanistic scheme was created using Figdraw.

#PolylacticAcid is a #biodegradable #plastic that can be broken down into oligomeric lactic acid (OLA) #nanoplastics. This study shows that OLA particles can accumulate in mouse #placenta & #fetus, inducing placental vascular dysplasia & fetal growth restriction @plosbiology.org 🧪 plos.io/4bR4e6W

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Ping Pong is on the bottom of me and Dave is on top of me. They’re both vaginally penetrating me (double vaginal). Our noses are bleeding due to a side effect of sex drive boosting drugs we got high on. I am blindfolded and I also have a purple ball gag in my mouth.

Ping Pong is on the bottom of me and Dave is on top of me. They’re both vaginally penetrating me (double vaginal). Our noses are bleeding due to a side effect of sex drive boosting drugs we got high on. I am blindfolded and I also have a purple ball gag in my mouth.

It is 9 months later and I’m giving birth to Dave and Ping Pong’s babies (I’m laying their eggs actually). Dave and Ping Pong are kissing each other and committing twincest while I am masturbating their penises for them as they’re leaking with a lot of pre-cum (because Dave and Ping Pong got quite sexually aroused when they were seeing me in labor and delivering their babies, or laying their eggs). Of course I am also straining in a lot of unbearable Level 9 excruciating pain as I’m pushing their huge eggs out of my vaginal opening, which is why I’m bleeding a little.

It is 9 months later and I’m giving birth to Dave and Ping Pong’s babies (I’m laying their eggs actually). Dave and Ping Pong are kissing each other and committing twincest while I am masturbating their penises for them as they’re leaking with a lot of pre-cum (because Dave and Ping Pong got quite sexually aroused when they were seeing me in labor and delivering their babies, or laying their eggs). Of course I am also straining in a lot of unbearable Level 9 excruciating pain as I’m pushing their huge eggs out of my vaginal opening, which is why I’m bleeding a little.

Dave and Ping Pong are now having some of the most biggest, powerful, and explosive orgasms of their lives as they’re cumming all over my whole body really hard and so much, that I’m completely covered in lots of their fresh hot semen. I am now in postpartum after laying their eggs. Dave and Ping Pong are panting and moaning really loud as they’re cumming and orgasming very profoundly together. I just knew the birthing process of their eggs was genuinely turning them on. Their newborn eggs have umbilical cords and placentas somehow…

Dave and Ping Pong are now having some of the most biggest, powerful, and explosive orgasms of their lives as they’re cumming all over my whole body really hard and so much, that I’m completely covered in lots of their fresh hot semen. I am now in postpartum after laying their eggs. Dave and Ping Pong are panting and moaning really loud as they’re cumming and orgasming very profoundly together. I just knew the birthing process of their eggs was genuinely turning them on. Their newborn eggs have umbilical cords and placentas somehow…

After Dave and Ping Pong’s eggs hatched, their babies were stillborn so they had to be aborted. Dave and Ping Pong are now in Dominatrix suits and they are torturing me together when I am restrained by 2 wrist cuffs with long chains suspended from rectangular ceiling bar/handles. Dave tortured me with a whip and Ping Pong tortured me with melted candle wax. I am also blindfolded alongside having a ball gag (but this time, the ball gag doesn’t have holes in it and it’s lavender colored instead of purple), just like the first image where Dave and Ping Pong were gang-banging me. My legs are restrained by my placentas that Dave and Ping Pong added heavy weights inside of. I have some explicit doodling on my body too, along with some scars, bruises, and burns.

After Dave and Ping Pong’s eggs hatched, their babies were stillborn so they had to be aborted. Dave and Ping Pong are now in Dominatrix suits and they are torturing me together when I am restrained by 2 wrist cuffs with long chains suspended from rectangular ceiling bar/handles. Dave tortured me with a whip and Ping Pong tortured me with melted candle wax. I am also blindfolded alongside having a ball gag (but this time, the ball gag doesn’t have holes in it and it’s lavender colored instead of purple), just like the first image where Dave and Ping Pong were gang-banging me. My legs are restrained by my placentas that Dave and Ping Pong added heavy weights inside of. I have some explicit doodling on my body too, along with some scars, bruises, and burns.

Dave and Ping Pong have really gotten into these types of Naughty kinks with me. I think they must really woo me. #camplazlo #dave #pingpong #loons #nsfw #selfship #selfinsert #sex #gangbang #orgasm #cum #semen #birth #postpartum #egglaying #bsdm #blood #placenta #piss #incontinence #abortion

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I would like to ask Mr. Ragusa. He mentioned that amount of #nanoplastics in #placenta has grown over decades. Do you have some data regarding it?

#antonioragusa #allatra #pregnancy

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What You Need to Know About Placental Function and Complications When a woman is pregnant, one of the most important organs responsible for sustaining the pregnancy is the placenta. It plays an essential role in providing nutrition and oxygen to the baby while in u...

What You Need to Know About Placental Function and Complications www.growingyourbaby.com/what-you-nee... #placenta #childbirth #pregnancy

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Muchas gracias por leer hasta el final 😊🙏🏼

¿Conocías este fenómeno tan poco frecuente de la medicina materno-fetal? 🤔

#obstetricia #placenta #embarazo #medicinafetal #oncologíaobstétrica

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How the Placenta Predicts Lifelong Health and Disease Risk Scientists are uncovering how the placenta, long viewed as a temporary pregnancy organ, acts as a powerful biological predictor of lifelong health, linking prenatal environments to future risks of car...

The placenta isn't just for pregnancy - it can shape your health for life! 🧬 Discover how placental structure and function predict lifelong disease risk, including heart and metabolic conditions. www.news-medical.net/health/How-t... #Placenta #MaternalHealth #Health

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#Article in #MedComm_Biomaterials_and_Applicaitons
#Myogenic Differentiation on 3D‐Printed Interpenetrating Bioactive #Hydrogel of Decellularised Human #Placenta With Fish Scale Gelatin

#bioactive #decellularization #HumanPlacenta

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What Is Fetal Microchimerism and How Does It Work? Fetal microchimerism is the presence of a small number of fetal cells that enter a mother’s body during pregnancy and persist for years or even decades. It happens when some fetal cells cross the placenta into the maternal bloodstream, settle in organs, and sometimes integrate into tissues. These cells may contribute to tissue repair in certain contexts, but they have also been associated with some autoimmune conditions, so their effects appear mixed.

Ever heard of fetal cells lingering in a mother long after birth? Learn how they travel, where they settle, and why they might help heal, or complicate, health. What would you ask a researcher? #AutoimmuneDisease #FetalMicrochimerism #Placenta #Pregnancy #TissueRepair

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COVID-19-related inflammation of the placenta impedes fetal development in pregnant hamsters - Nature Communications COVID-19 during pregnancy is still incompletely understood. Here, the authors use a hamster model to show that it causes placental inflammation, impairing fetal growth but without vertical transmissio...

🧪#COVID19-related #inflammation of the #placenta impedes fetal development in pregnant hamsters @natcomms.nature.com
#pregnancy www.nature.com/articles/s41...

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Would you get a penis facial? The Hollywood EGF (Epidermal Growth Factor) Facial? 🤔 & do you think it’s ironic we’ve been taught circumcision is “normal,” the cord should be cut immediately, & placentas are just biohazard trash..

🤥

#EGF #Circumcision #DelayedCordClamping #Placenta #UmbilicalCord

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MultiSearch Tag Explorer MultiSearch Tag Explorer - Explore tags and search results by aéPiot

#SINIŠA #KARAN
aepiot.com/advanced-sea...
#MINISTARSTVO #UNUTRAŠNJIH #POSLOVA #REPUBLIKE #SRPSKE
aepiot.com/advanced-sea...
#PLACENTA #ACCRETA
multi-search-tag-explorer.aepiot.ro/advanced-sea...
aepiot.com

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The new metric also helps #unify earlier debates about microbiomes reported in #placenta and #blood. When we reanalyzed long-read data from those settings using the same read length-based approach, we found no evidence for a stable resident microbiome under normal conditions, consistent with the 9/

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Un resultado muy interesante y que muestra cómo el espermatozoide puede influir en el embarazo: la edad paterna está relacionada con cambios similares en el metiloma del espermatozoide y de la placenta.
onlinelibrary.wiley.com/doi/10.1111/...
#bianorbiotech #epigenetics #MaleFertility #placenta

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Researchers link Alzheimer’s disease protein to preeclampsia Study sheds new light on leading cause of medically-induced premature birth

Researchers have discovered that amyloid-β deposits - similar to those found in #Alzheimers disease - disrupt the formation of the #placenta and may therefore contribute to the development of #preeclampsia during #pregnancy. Their insights are published in @lsajournal.org.

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‼️📢 Preprint Alert 📢‼️

Pleased our work investigating Prader-Willi syndrome #PWS gene expression in #placenta is finally in wild! This represents a huge effort from lots of talented students with support from excellent collaborators and the brilliant #FPWR

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This review examines the evolution of the gut-placenta axis over the past 50 years and looks forward to its clinical translation in the next 50 years.
doi.org/10.59717/j.x...
#MaternalObesity #gutmicrobiota #placenta

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α7 Nicotinic acetylcholine receptor activation rescues mitochondrial dysfunction in gestational diabetes mellitus by competing with p66Shc for VDAC1 binding - Diabetologia Aims/hypothesis Gestational diabetes mellitus (GDM) is associated with placental hormone-induced insulin resistance; however, the mechanisms connecting hyperglycaemia to mitochondrial dysfunction rema...

α7nAChR activation reverses placental mitochondrial dysfunction in gestational diabetes, revealing a potential novel #therapy. By Lulu Ji, Lin Wang et al #GDM #Mitochondria #Placenta link.springer.com/article/10.1...

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New paper 🌟✨

We found that some placentas age too early in stillbirth - linked to circular RNAs, DNA damage, and cell stress.

Crucially, these signals can show up early in pregnancy, in blood.

Small molecules, big clues!

#Stillbirth #Placenta #PregnancyResearch
🔗 below

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#humanity #nature #placenta #nanoplastic #microplastic

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El consumo de placenta podría ayudar a combatir los síntomas de la menopausia Dentro de los nuevos tratamiento alternativos para la menopausia se encuentra el consumo de placenta y un reciente estudio indaga acerca de sus efectos  ...

El consumo de #placenta podría ayudar a combatir los síntomas de la #menopausia

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Worth watching, interview by @democracynow.org with Judith Enck, @beyondplastics.bsky.social, about #plastic #pollution #climate #crisis #cancer #poverty #microplastics #oceans #fossil #fuels #pfas #placenta #babies #testicles #breast #food #forever #chemicals @exxonmobiloil.bsky.social #shell etc.

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VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment | PNAS The trophectoderm (TE), the first lineage specified during mammalian development, initiates implantation and gives rise to placental trophoblasts. ...

And the open access article in PNAS
#ReproSky #placenta #Development
www.pnas.org/doi/10.1073/...

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Researchers uncover the earliest stages of human placenta formation A gene that turns on very early in embryonic development could be key to the formation of the placenta, which provides the developing fetus with what it needs to thrive during gestation.

“They discovered that a gene called VGLL1 (vestigial like family member 1) was turned on very early during placenta formation. It was key to the process of turning pluripotent stem cells into various types of placental stem cells”
#placenta #ReproSky #Development
medicalxpress.com/news/2025-12...

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Robert Pijnenborg – An appreciation
#Placenta #Trophoblast #ReproSky #Science #Pregnancy
www.sciencedirect.com:5037/science/arti...

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Studie legt #Endocytose als 2ten Infektionsweg für SARS-Cov-2 in der #Placenta nah

Dh
Wenn sie als Frau beschlossen haben in der Schwangerschaft nicht zu rauchen und zu saufen sollten sie dieses Programm um Maske sowie zumindest eine Impfung ergänzen

www.tandfonline.com/doi/pdf/10.1...

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Prenatal fructose exposure independently impacts placental phenotype and female offspring kidney function and liver composition in rats Archaeological and anthropological evidence suggests that human ancestors' diets were rich in fiber, potassium, and complex carbohydrates, while low in sodium, refined sugars, and energy density.…

Inter-generational #physiology: Study of effects of excessive #maternal #fructose intake on the #placenta and offspring in a rat model reports effects on placental anatomy and sex-specific effects on #kidney and #liver function in adult offspring.
doi.org/10.14814/phy...
#Metabolism

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I am the woman with the half teal half neon pink hair that is laying down on the blue couch. Val is the surreal looking man with 2 mouths that is penetrating and seeding me. The character out his window in the black void is a man that Val calls “FaceHead” in the “Val Val Val” animation from 2009. On the upper right corner of this image displays a cross section view of Val ejaculating his semen into my uterus. On the upper left corner of this image displays a cross section view showing his sperm fertilizing my ovum and turned it into an embryo, resulting in pregnancy. Val’s room is beige with a grey floor and a grey ceiling. Behind him is a thin brown window frame where FaceHead stands outside while watching us breed on the blue couch in sexually aroused shock. There is a huge puddle of semen under Val and I and it got all over the couch.

I am the woman with the half teal half neon pink hair that is laying down on the blue couch. Val is the surreal looking man with 2 mouths that is penetrating and seeding me. The character out his window in the black void is a man that Val calls “FaceHead” in the “Val Val Val” animation from 2009. On the upper right corner of this image displays a cross section view of Val ejaculating his semen into my uterus. On the upper left corner of this image displays a cross section view showing his sperm fertilizing my ovum and turned it into an embryo, resulting in pregnancy. Val’s room is beige with a grey floor and a grey ceiling. Behind him is a thin brown window frame where FaceHead stands outside while watching us breed on the blue couch in sexually aroused shock. There is a huge puddle of semen under Val and I and it got all over the couch.

This illustration depicts 9 months later, I’m giving Unmedicated natural vaginal childbirth to Val’s baby that is so big, it gave me a 3rd degree tear. I got lots of blood all over the giant training pad while I kept pushing it out. If you’re wondering what my face looks like in case You’re blind, that’s just me screaming in excruciating pain from severe labor contractions and vaginal tearing. My maternity gown is lavender colored. The color of bed sheet is pastel sage green. The color of the hospital bed frame is pastel lavender. The color of the metallic handle bars on the hospital bed are silver. The wall tiles are pastel pink and the hardwood floor is light brown.

This illustration depicts 9 months later, I’m giving Unmedicated natural vaginal childbirth to Val’s baby that is so big, it gave me a 3rd degree tear. I got lots of blood all over the giant training pad while I kept pushing it out. If you’re wondering what my face looks like in case You’re blind, that’s just me screaming in excruciating pain from severe labor contractions and vaginal tearing. My maternity gown is lavender colored. The color of bed sheet is pastel sage green. The color of the hospital bed frame is pastel lavender. The color of the metallic handle bars on the hospital bed are silver. The wall tiles are pastel pink and the hardwood floor is light brown.

This is me, back from the hospital in postpartum. Having vaginal sex with Val again. But this time, we have such bloody postpartum sex that it got our inner thighs all bloody and I stained yet another giant training pad with tons of lochia blood. Val pumped the crap out of me and shot lots of his semen up into my postpartum uterus while I orgasm so hard, I have urinary incontinence. On the upper right corner on this image displays an internal cross section of Val’s penis inside of my vaginal canal and ejaculating his semen into my uterus. The bottom left corner of the image displays an external cross section view showing the full frontal close-up of what our genitals look like during sex.

This is me, back from the hospital in postpartum. Having vaginal sex with Val again. But this time, we have such bloody postpartum sex that it got our inner thighs all bloody and I stained yet another giant training pad with tons of lochia blood. Val pumped the crap out of me and shot lots of his semen up into my postpartum uterus while I orgasm so hard, I have urinary incontinence. On the upper right corner on this image displays an internal cross section of Val’s penis inside of my vaginal canal and ejaculating his semen into my uterus. The bottom left corner of the image displays an external cross section view showing the full frontal close-up of what our genitals look like during sex.

I’ve been really into this Weird YouTube video I found called “Val Val Val” created by Ben Wheele. #SelfInsert #SelfShip #ValValVal #BenWheele #NSFW #Sex #Orgasm #Cum #Birth #Postpartum #Placenta #Piss #Incontinence #Blood #Squirting #Semen #LaborPains #Ahegao

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