Did you miss #EMBLSpatialBiology? Check out our blog by event reporter Karina Barreiro to explore the research presented at the conference from the perspective of a scientist just starting in the field.

🔗 www.embl.org/about/info/course-and-co...

And from Heidelberg at the #EMBLSpatialBiology we can report that Ellen Schrader, a PhD student in the Lab, won one of the poster prizes. #ESSB2025
Congratulations!

And that’s a wrap #EMBLSpatialBiology #ESSB2025

✨ #EMBLSpatialBiology has come to an end!

A huge thank you to all the participants, speakers, organisers, and industry partners who made this event unforgettable. A special thanks to the ESSB for co-organising this inspiring meeting.

See you at the next EMBL event 👉 embl.org/events

#ESSB2025

Imaging-based multimodal profiling of single cells with STAMP - Nature Reviews Genetics In this Tools of the Trade article, Kellie Wise and Anna Pascual-Reguant introduce STAMP (single-cell transcriptomics analysis and multimodal profiling), which harnesses imaging to measure RNA and/or ...

Wow, @pascual-reguant.bsky.social, very impressive talk at #EMBLSpatialBiology! Presented preprint with @hoheyn.bsky.social: www.biorxiv.org/content/10.1...
You can also read more on the STAMP technology in @natrevgenet.nature.com: www.nature.com/articles/s41... 🧪

Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology Alterations in transactivating response region DNA-binding protein 43 (TDP-43) are prevalent in amyotrophic lateral sclerosis (ALS), frontotemporal de…

Very interesting talk by @orrlaboratory.bsky.social at #EMBLSpatialBiology. In preparation, I read their recent paper, and found some decent astrocyte signalling and proteinopathy in it 👇🏻👇🏻 www.sciencedirect.com/science/arti... 🧪

Thanks for the pics Josh! Such a great meeting at #EMBLSpatialBiology

Participants at #EMBLSpatialBiology are making the most of Day 4!

After a morning of talks on data analysis in spatial biology, they are now exploring exciting new tech at the industry exhibition and recharging with coffee. ☕🤝

Stop by our posters this evening at #EMBLSpatialBiology #ESSB2025:
- @kbestak.bsky.social , Poster 48
- @margotch.bsky.social, Poster 96
- @miguelib.bsky.social, Poster 108
- @chiaraschiller.bsky.social, Poster 188
- @natgabrielli.bsky.social from @mspacealliance.bsky.social, Poster 90

Just watching mindblowing talk from Ralf Jungmann at #EMBLSpatialBiology meeting on pushing imaging to single molecule resolution and the insights it drives. Astonishing work!!!

If you missed @chiaraschiller.bsky.social’s talk at #EMBLSpatialBiology you can catch her at Poster 188 this evening

We're having an amazing time at the European Spatial Biology Conference @events.embl.org! Stop by our booth through Friday to explore how #AVITI24 5D #multiomics unites RNA, morphology, protein, and dynamic response for a truly connected view of biology. #EMBLSpatialBiology #ESSB2025

We are at the #EMBLSpatialBiology: Melting Pot in beautiful Heidelberg this week!

Exciting poster session today where also Matthias and Adrian shared their work.

#ESSB2025

✨ Poster session time at #EMBLSpatialBiology!

There's nothing like the energy of scientists coming together to share new ideas. So much creativity pushing spatial biology ahead! 🚀

#ESSB2025

Are you at #EMBLSpatialBiology #ESSB2025? Catch our posters this evening:
- Nils Englert, Poster 83
- @arojhada.bsky.social, Poster 97
- @loggas.bsky.social, Poster 185
- @jawadalaaedeen.bsky.social, Poster 187

A computational pipeline for spatial mechano-transcriptomics - Nature Methods The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.

Awesome talk by @halloulab.bsky.social at #EMBLSpatialBiology. May the force be with you in biophysical phenotypes of spatial transcriptomics; out now in @natmethods.nature.com: www.nature.com/articles/s41... 🧪

Excited to be at #EMBLSpatialBiology #ESSB2025 this week and present our new 3D imaging and analysis pipeline ‘LeGO-3D’

@sergiosdhi.bsky.social takes to the #ESSB2025 stage to demonstrate TopROI, a new mathematical tool for preserving structure when dividing large point clouds into multiple regions of interest! #EMBLSpatialBiology

LeGO-3D: 3D imaging of lung metastases and vascularisation using light sheet fluorescence microscopy Cancer metastasis involves a complex cascade of events, where cancer cells migrate from their site of origin to secondary sites via the lymphatic and circulatory system. During this process, some canc...

Stunning, what @sabrinalewis.bsky.social just showed at #EMBLSpatialBiology! LeGO depicts cell populations in lung metastases in 3D: www.researchsquare.com/article/rs-6... 🧪 Soon out in npj Imaging @natureportfolio.nature.com

Welcome to Day 2 of #EMBLSpatialBiology!

We’re looking forward to a full day of talks on spatial immunology and the latest advances in spatial biology.
If you’re on site, don’t miss the industry workshops and our first poster session later today! 🎉

#ESSB2025

Great to see some exciting applications of #MuSpAn in action in @pathologop.bsky.social's talk at #ESSB2025 today!

Come and say hi if you'd like to find out more about the software, or to have a chat about how MuSpAn might be able to help with your data analysis :) #EMBLSpatialBiology

The tumour histopathology “glossary” for AI developers The applications of artificial intelligence (AI) and deep learning (DL) are leading to significant advances in cancer research, particularly in analysing histopathology images for prognostic and treat...

Really cool talk (even though confidential) by @pathologop.bsky.social at #EMBLSpatialBiology!
So let's look at his tumour histopathology “glossary” for AI developers in @plos.org Comp Biol:
journals.plos.org/ploscompbiol... 🧪

Day 2 at Spatial biology: the melting pot #EMBLSpatialBiology

Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer - Nature Genetics This study uses spatial proteomic and spatial compartment-based whole-transcriptome profiling to develop predictive models for immunotherapy outcomes in non-small cell lung cancer.

Very cool talk by @aruthak.bsky.social at #EMBLSpatialBiology!
Spatial signatures predict immunotherapy outcome in non-small cell lung cancer, out in @natgenet.nature.com: www.nature.com/articles/s41... 🧪

✨Full house for our first keynote speaker, Jeffrey Spraggins, Vanderbilt University, USA, presenting 'Bringing disease into focus with integrative multimodal imaging mass spectrometry'.

A powerful start to #EMBLSpatialBiology!

STAMP: Single-cell transcriptomics analysis and multimodal profiling through imaging Single-cell transcriptomics analysis and multimodal profiling (STAMP) by imaging enables single-cell analysis of cells in suspension without the need for sequencing. The markedly reduced costs and fle...

The one-and-only @hoheyn.bsky.social showcases "the power of millions" using (sub-)STAMP Imaging at #EMBLSpatialBiology @cp-cell.bsky.social
www.cell.com/cell/fulltex... 🧪

Lorenz in front of a screen with live stream

Too bad I couldn’t make it in person to beautiful Heidelberg, but virtual participation from home is definitely the second-best option! #EMBLSpatialBiology

Just pulling into Heidelberg for #EMBLSpatialBiology #ESSB2025... Really looking forward to meeting more of the #SpatialBiology community this week!

If you want to chat with a friendly mathematician, do say hi if you see me wandering around, or drop me a message on here and we can coordinate :)

Are you ready to kick off #EMBLSpatialBiology? 🚀

📷 Participants are already filling the ATC with energy here at EMBL Heidelberg!

Stay tuned for highlights, behind-the-scenes moments, and the latest in #SpatialBiology 👀

We’re excited to be at @embl.org this week for Spatial Biology: the melting pot. We’re looking forward to hearing about some awesome science 🔬 #EMBLSpatialBiology