Researchers establish a full-length #gallbladder #transcriptome atlas using #LongReadSequencing and identify ERBB2 i14e as a novel isoform driving #TumorGrowth and trastuzumab resistance. #ERBB2 #antisense #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

This long-term analysis of the ShortHER trial (10-year data, 866 pts) highlights the crucial role of tumor-infiltrating lymphocytes #TILs in ERBB2-positive early breast cancer.

@jama.com @bccroc.bsky.social

#Onco404 #Cancer #Kanser #BreastCancer #MemeKanseri #ERBB2 #HER2 #MedSky #OncSky

💡 Boosting Perioperative Therapy for ERBB2+ Gastric/GEJ Cancer?

This phase 2 randomized trial investigated adding immunotherapy (atezolizumab) to standard perioperative trastuzumab + XELOX chemotherapy 🔬

#Onco404 #Cancer #Kanser #MedSky #OncSky #GastricCancer #Immunotherapy #ERBB2 #ClinicalTrials

Featured today by @MSKLibrary: Survival Among Patients With ERBB2-Positive Metastatic Breast Cancer and Central Nervous System Disease

#ERBB2 #MetastaticBreastCancer #CNSMetastases #BreastCancerResearch #SurvivalOutcomes

jamanetwork.com/journals/jam...

Study from Memorial Sloan Kettering reveals that patients with ERBB2-positive metastatic breast cancer and CNS metastases have longer overall survival but remain at high risk for CNS-related death. Aggressive treatments may be needed. #BreastCancer #ERBB2 ascopost.com/news/februar...

Digital PCR quantification of ultrahigh ERBB2 copy number identifies poor breast cancer survival after trastuzumab - npj Breast Cancer npj Breast Cancer - Digital PCR quantification of ultrahigh ERBB2 copy number identifies poor breast cancer survival after trastuzumab

Our new publication online today on dPCR quantification of “#ultrahigh” #HER2 #ERBB2 copy number in early #breastcancer and association to poor response to #trastuzumab. Nice work by #pei_meng #heena_dilal @brueffer.io #sergii_gladchuk #anna_ehinger et al www.nature.com/articles/s41...