Berger Montague Begins Investigation into Akero Therapeutics for Possible Breaches of Duty #United_States #San_Francisco #Berger_Montague #Akero_Therapeutics #Efruxifermin
Potential Legal Trouble Looms for Akero Therapeutics as Berger Montague Launches Investigation #USA #San_Francisco #Berger_Montague #Akero_Therapeutics #Efruxifermin
Investigation Launched into Akero Therapeutics Over Board Misconduct and Securities Violations #USA #San_Francisco #Berger_Montague #Akero_Therapeutics #Efruxifermin
More #efruxifermin data this time in #MASH F2/F3 fibrosis @ 96 weeks
✅ Efficacy w/ dose dependent response (sort of) and NITs consistent
↔️ not crazy about mITT though it is mentioned no paired bx= non responders
⬇️ dose dependent reduction in bone mineral density
#liversky
MetaVia's DA-1241 and Efruxifermin Show Promising Results in Combating MASH #USA #Chicago #MetaVia #DA-1241 #Efruxifermin
Great news for persons w/ #MASH cirrhosis in this ph2b study of #efruxifermin
Thoughts:
🤞it is a fair statement that longer rx may yield better results but that remains to be proven
the authors are to be 👏 for presenting ITT data. MASH studies needs to move away from “completer” analyses
#liversky
96 wk #efruxifermin @akerotx
HARMONY trial:
“Paired biopsy set”
🔥 46-75% vs. 24% fibrosis improvement
ITT
🙁 30-49% vs. 20%
Up to 7 kPa ⬇️ in VCTE
No weight change
Some reduction in BMD
“Unprecedented” fibrosis improvement but not in ITT
@easlcongress @livertwitter