📝 Available online - the Review "The nuclear export receptor CRM1/XPO1 and its diverse cargoes" from Ralph Kehlenbach and @yuhminchook.bsky.social.

#CRM1 #Exportin1 #NuclearTransport #NuclearPoreComplex #RNAExport

Read it here: authors.elsevier.com/sd/article/S...

The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition The HIV nuclear export complex shows that CRM1 recognizes diverse cargos through distinct sites, utilizing multipartite recognition via the NES and additional protein and RNA contacts. A unique CRM1 d...

Beautiful work! RRE binds CRM1. Wow! 😊
#HIV1 #Rev #RRE #CRM1 #Exportin1 #Ran

www.cell.com/molecular-ce...

Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex Many genes physically interact with the nuclear pore complex (NPC), which requires transcription factors (TFs). Ge et al. show that the exportin Crm1 binds TFs and nuclear pore proteins to dock chroma...

Cool! New role for #Exportin1 #Crm1 #Xpo1
#Adaptor #NuclearPore #NPC #TranscriptionFactor

Exportin-1 functions as an adaptor for transcription factor-mediated docking of chromatin at the nuclear pore complex: Molecular Cell www.cell.com/molecular-ce...