Researchers outline key features and detection advances of #ExtrachromosomalCircularDNA, showing how long-read sequencing unlocks #eccDNA’s potential as stable #biomarkers for #cancer, #DrugResistance monitoring, #PrenatalTesting, and immune diseases.

#OpenAccess: doi.org/10.1016/j.ge...

Extrachromosomal circular DNA and their roles in cancer progression

This review provides an overview of the biogenesis, distinguishing features, and functions of #ExtrachromosomalCircularDNA (eccDNA), its role and mechanisms during cancer treatment, and highlights its potential for precision #CancerTherapy. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...