Platelet-Activating Anti-HPA-1a Antibodies Drive Pathogenic Mechanisms in FNAIT According to recent research, a subset of anti-HPA-1a antibodies directly activated human platelets via FcγRIIa, suggesting added pathogenicity in FNAIT.

Fetal and neonatal alloimmune thrombocytopenia (#FNAIT) is a potentially life-threatening condition with a distinct subset of antihuman platelet antigen 1a antibodies that can directly activate platelets through #FcγRIIa. @ash.hematology.org

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