🟢The crystal structure of the green fluorescent protein, GFP! 🟢
The chromophore is yellow. The protein rigidizes the chromophore, releasing energy as fluorescence.
🎥I made the movie with UCSF Chimera & 1EMA.pdb.
#FluorescenceFriday #FluorescentProtein #GFP #SciComm

Fluorescent “superheroes”！ mBaoJin + mScarlet3-H (also known as mYongHong) Tool Viruses Empower Super-Resolution and High-Efficiency Imaging Discover Brain Case Biotech's viral vectors with mBaoJin and mScarlet3-H proteins, offering superior photostability and precise delivery for advanced imaging in cell biology and neuroscience.

🎉 Fluorescent “superheroes”！
📍Tired of photobleaching and weak signals limiting your imaging?
Explore the full product list, from synaptic labeling to mitochondrial markers, via the link below!
www.ebraincase.com/news/new-pro...

#Neuroscience #CellBiology #SuperResolution #FluorescentProtein #AAV

A #fluorescencefriday — just in time for Valentine's Day! ❤️

The Godwin Lab at MDI Bio Lab perfects a new method of illuminating the #axolotl heart with a red #fluorescentprotein to simplify the identification of animals with gene deletions during embryonic development.

🧪 🧬 #microscopy

💫🧬🧫Fluorescent proteins make the holidays!🧫🧬💫

The Roger Y. Tsien lab (UCSD) made the wreaths with fluorescent proteins!🖌️🎨

#FluorescenceFriday #SciArt #AgarArt #MicrobialArt #BioArt #FluorescentProtein #FluorescentProteins

dear #fluorescentprotein specialists: anybody knows if mStaygold can be used in split complementation assays? Is analogy to the s11 strand split possible?

Sensitive red fluorescent indicators for real-time visualization of potassium ion dynamics in vivo Despite recent advances in green genetically encoded potassium indicators (GEPOs), developments in red-shifted GEPOs have been slower. These authors engineer two new red fluorescent potassium indicato...

Our latest paper in PLoS Bio, where we support with describing the mechanism of new red K+ sensors with MD! We found a new binding site that explains the sensitive turn-on response and selectivity against Ca, among other fun insights #chemsky #fluorescence #fluorescentprotein
doi.org/10.1371/jour...

Scientists made a biological quantum bit out of a fluorescent protein Researchers could use quantum effects to develop new types of medical imaging inside cells themselves.

Scientists made a biological quantum bit out of a fluorescent protein #Science #Physics #QuantumPhysics #QuantumComputing #FluorescentProtein #BiologicalQuantumBit

🔬🦠Bacterial chemotaxis!🦠🔬
Students imaged bacteria expressing the small Ultra-Red Fluorescent Protein (smURFP) to follow attraction to sugars & repulsion to glycine.🍬
#FluorescenceFriday #Microbiology #Chemotaxis #FluorescentProtein #SciComm

🌊The beautiful fluorescence of a sea anemone!🌊

#FluorescenceFriday #FluorescentProtein #Coral #Sea #Ocean

✨🌟The 3D printed structure of Discosoma red fluorescent protein (DsRed)!🌟✨
The red chromophore is fluorescent due to rigidification by the white beta-barrel.
#FluorescenceFriday #SciArt #FluorescentProtein

A twisted chromophore powers a turn-on fluorescent protein chloride sensor | PNAS Fluorescent proteins (FPs) are noninvasive genetically encodable probes that have revolutionized bioimaging and health fields with vivid images and...

www.pnas.org/doi/10.1073/... very proud of this work where we demonstrate that a rigid but twisted chromophore can be highly fluorescent, and part of a turn-on response! Beautiful QM/MM work from my student, Vishaka #chemsky #fluorescentprotein

This #microscopymonday image from @hsomers.bsky.social
@mdibl-lmf.bsky.social shows endothelial cells of a #renal organoid interwoven with laminin. Magenta shows laminin (mCherry) and yellow shows CD31 (a Green #FluorescentProtein). 🧪 🤝

#standwithscience #researchmatters #microscopy #lightsheet

🎨🖌️🧫🧬🦠Smurfette painted with E. coli expressing EGFP (yellow) or small Ultra-Red Fluorescent Protein (cyan).🦠🧬🧫🖌️🎨
The name smURFP is inspired by the purified protein.
#FluorescenceFriday #SciArt #AgarArt #SciComm #FluorescentProtein #FluorescentProteins #smURFP

New mYongHong, a super stable monomeric red fluorescent protein, is here for high-res imaging! 🔬✨ Perfect for neuroscience and cell bio research. 🧠🔴 Check it out now! 👀👇
www.ebraincase.com/news/new-pro...

#FluorescentProtein
#BrainResearch
#BrainCase
#Neuroscience
#CellImaging
#NatureMethods

The structural features responsible for the greatly improved fluorescent performance of the photoconvertible fluorescent protein pcStar are revealed #FluorescentProtein #Photoconvertible #PcStar doi.org/10.1107/S205...

mScarlet3-M163H/M66Q #FluorescentProtein #GFP is reported as an exceptionally photostable red FP. I'm wondering if any of you have practical experience with it yet?

@steveroyle.bsky.social @franbottanelli.bsky.social @joachimgoedhart.bsky.social @christlet.bsky.social @manorlaboratory.bsky.social

🌦️On days like these, I miss the sun!🌦️
🌞Justin Hachey painted the sun with E. coli expressing the small ultra-red fluorescent protein, smURFP. 🧫🦠🧬🌞
#FluorescenceFriday #FluorescentProtein #Microbiology #Bacteria #AgarArt #SciArt

zebrafish muscle under a microscope

"Muscle Power"

This image by Assistant Prof. Romain Madelaine & Research Assistant Caroline Halluin in 2021, depicts muscle tissue in #zebrafish; green slow fibers, magenta fast fibers & red mitochondria in skeletal muscle fibers are lit up using #fluorescentprotein technology. 🧪🤝 #microscopymonday

PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

📜 Red fluorescent proteins engineered from green fluorescent proteins

🧑‍🔬 Hiromi Imamuraa, Shiho Otsubob, Katsumi Imada, et al.

📔 PNAS

🔗 www.pnas.org/doi/10.1073/...

#️⃣ (Feeds) #Microscopy

🔊 Conversion of a green into a red #FluorescentProtein has always been problematic, finally it worked!