🚨Job alert!
🔬We have 2 new open positions (1 PhD, 1 postdoc) in our team (santosmorenolab.org) in Barcelona @upf.edu @prbb.org funded by @erc.europa.eu
If you are passionate about #SynBio and #GeneCircuits, apply now! (until Oct. 26th) 🦠🔧
Info below 👇Please RT!

How Evolution Rewires Gene Circuits to Create New Biological Patterns

Recent research shows evolution reshapes gene circuits, allowing new patterns like stripes and spots, and swapping regulatory elements between species can reproduce donor traits. getnews.me/how-evolution-rewires-ge... #evolution #genecircuits

CRISPRi-Linked Multi-Module Negative Feedback Loops to Address Winner-Take-All Resource Competition Cellular resource limitations create unintended interactions among synthetic gene circuit modules, compromising circuit modularity. This challenge is particularly pronounced in circuits with positive ...

🆕 Another preprint!
CRISPRi-linked multi-module negative feedback loops to combat winner-take-all dynamics from resource competition in gene circuits.
📄 www.biorxiv.org/content/10.1...
#SynBio #CRISPRi #GeneCircuits #ResourceCompetition

Integrating Recombinase-Based Feedback and Feedforward Control for Optimal Resource Decoupling Resource competition disrupts circuit modularity by introducing unintended coupling between otherwise independent gene modules, thereby compromising genetic circuit function. While various control str...

🚨 New preprint!
We present Re-NF-FF-Controller—a compact strategy that integrates negative feedback and feedforward control via a single promoter flip to optimally decouple resource competition.
📄 www.biorxiv.org/content/10.1...
#SynBio #GeneCircuits #ResourceCompetition

🚨We have a fully funded open PhD position in bacterial synthetic biology available in our lab (www.yschaerli.com) in beautiful Lausanne, Switzerland @dmf-unil.bsky.social @fbm-unil.bsky.social @unil.bsky.social
If you are passionate about #SynBio and #GeneCircuits, apply here: tinyurl.com/mry2xwa5

On #WorldCancerDay, we acknowledge the stories behind every cancer diagnosis—resilience, loss, hope, and healing. These stories drive us to develop intelligent #GeneCircuits for next-gen cell and #genetherapies, aiming to transform outcomes for cancer patients. #UnitedByUnique

Synthetic memory circuits for stable cell reprogramming in plants Nature Biotechnology - Transcriptional activity in plants is controlled with a programmable gene circuit.

Great talk by @jamespblloyd.bsky.social today using Recombinases to produce #GeneCircuits for #Plants. Lots of interesting potential uses for #Biotech and fundamental #Science! Covered lots of info from his paper: rdcu.be/dSuHu