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GlycoRNA biology, a naive field with unlimited horizons GlycoRNA biology, a naive field with unlimited horizons

GlycoRNA biology, a naive field with unlimited horizons
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Enhanced anti-proliferative activity of Jacalin, a plant lectin in combination with taxol in MDA-MB-468 triple-negative breast cancer cells Plant lectins derived from a variety of plant sources can inhibit the proliferation of certain types of human cancer cells and have been studied extensivel

Enhanced anti-proliferative activity of Jacalin, a plant lectin in combination with taxol in MDA-MB-468 triple-negative breast cancer cells
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Salmon proteoglycan modulates TIMP–gelatinase regulation in intestinal epithelial cells Chondroitin sulfate (CS) and CS proteoglycans (CSPGs) are increasingly used in nutritional and biomedical applications. Although their functional benefits

Salmon proteoglycan modulates TIMP–gelatinase regulation in intestinal epithelial cells
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Identification of mitochondrial associated genes as diagnostic biomarkers for basal cell carcinoma: Comprehensive bioinformatics analysis and experimental validation The aim of our research was to explore and validate the diagnostic value of mitochondria-related genes (MRGs) in basal cell carcinoma (BCC). The d

Identification of mitochondrial associated genes as diagnostic biomarkers for basal cell carcinoma: Comprehensive bioinformatics analysis and experimental validation
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Total plasma N-glycomic patterns of COVID-19 disease Total plasma N-glycans alter in disease states, with few studies focused on COVID-19. A discovery cohort of 310 COVID-19 patients, replicated with 97 COVID

Total plasma N-glycomic patterns of COVID-19 disease
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Isolation and structural elucidation of immunomodulatory oligosaccharides from Trillium tschonoskii Six oligosaccharides with the degree of polymerization (DP) 2 to 7 were isolated from the active fraction of Trillium tschonoskii using a high-temperature

Isolation and structural elucidation of immunomodulatory oligosaccharides from Trillium tschonoskii
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Review on macrophage polarization during visceral leishmaniasis and impact of glycoprotein Visceral Leishmaniasis is one of the neglected vector-borne tropical disease escalating resistance against available drugs which have toxicity beyond thera

Review on macrophage polarization during visceral leishmaniasis and impact of glycoprotein
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SPR interaction analysis of GM3 glycan with the integrin α5β1 head domain Integrins are heterodimeric receptors involved in cell adhesion and bidirectional signaling. Ganglioside GM3 in the outer leaflet of cell membranes possibl

SPR interaction analysis of GM3 glycan with the integrin α5β1 head domain
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Integrating plasma protein-centric multi-omics to evaluate the causal effect of glycosylation on the risk of cancer Glycosylation is a crucial post-translational modification, and numerous studies have reported its significant role in cancer progression. Nevertheless, no

Integrating plasma protein-centric multi-omics to evaluate the causal effect of glycosylation on the risk of cancer
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Assessment of IgG N-Glycan patterns in adult patients with immune thrombocytopenia and healthy individuals Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by a platelet count less than 100,000/μL caused by increased immune-med

Assessment of IgG N-Glycan patterns in adult patients with immune thrombocytopenia and healthy individuals
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Mass spectrometric profiling reveals alterations in N-Glycans and O-Glycans in Tay-Sachs disease under Autophagy-Induced conditions Tay-Sachs disease is a rare neurodegenerative disorder caused by mutations in the HEXA gene. The HEXA gene encodes the α-subunit of the enzyme β-

Mass spectrometric profiling reveals alterations in N-Glycans and O-Glycans in Tay-Sachs disease under Autophagy-Induced conditions
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High molecular weight fucosylated glycosaminoglycan promotes the binding of antithrombin and thrombin: a template mechanism and structure-activity relationship study Native fucosylated glycosaminoglycan (FG), a structurally unique polysaccharide with chondroitin sulfate like backbone and sulfated fucose side chains, has

High molecular weight fucosylated glycosaminoglycan promotes the binding of antithrombin and thrombin: a template mechanism and structure-activity relationship study
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Identification of a distinct sialic acid (KDN) and a KDN-specific aldolase in Pacific oyster Sialic acids are a diverse family of acidic sugars typically found at the terminal positions of glycan chains, mediating key physiological and pathological

Identification of a distinct sialic acid (KDN) and a KDN-specific aldolase in Pacific oyster
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In Silico and in vitro evaluation of Cucurbitaceae seed lectins as promising prophylactic and therapeutic agents against SARS-CoV-2 Concern over COVID-19 has arisen from continuous mutations in SARS-CoV-2 genome leading to emergence of novel variants. A detailed study and understanding

In Silico and in vitro evaluation of Cucurbitaceae seed lectins as promising prophylactic and therapeutic agents against SARS-CoV-2
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Eukaryotic expression and characterization of two α1,2-fucosyltransferase genes in the histo-blood group antigens synthesis pathway of the Pacific oyster (Crassostrea gigas) Norovirus (NoV), an important cause of human viral gastroenteritis worldwide, recognizes human histo-blood group antigens (HBGAs) as receptors. Oysters are

Eukaryotic expression and characterization of two α1,2-fucosyltransferase genes in the histo-blood group antigens synthesis pathway of the Pacific oyster (Crassostrea gigas)
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Monoclonal antibody-based assay to identify compounds that inhibit Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) formation The advanced glycation end-product Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) accumulates during the progress of atherosclerosis with type 2 diabe

Monoclonal antibody-based assay to identify compounds that inhibit Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) formation
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Advanced glycation end products (AGEs) and their role in diabetes mellitus and related complications: mechanisms and therapeutic insights Diabetes mellitus (DM) is marked by prolonged elevated blood glucose levels, which lead to the formation of covalent adducts between glucose and plasma pro

Advanced glycation end products (AGEs) and their role in diabetes mellitus and related complications: mechanisms and therapeutic insights
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Cell cycle regulation in cancer cells by O-GlcNAcylation Cancer remains one of the leading causes of death worldwide. Due to the multiple molecular mechanisms involved in cell transformation, its biology continue

Cell cycle regulation in cancer cells by O-GlcNAcylation
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Effects of GM1 ganglioside and its derivatives on ETI-rescued F508del-CFTR maturation and host-pathogen interactions in cystic fibrosis bronchial cells Cystic Fibrosis (CF), a life-threatening hereditary disease, arises from mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene,

Effects of GM1 ganglioside and its derivatives on ETI-rescued F508del-CFTR maturation and host-pathogen interactions in cystic fibrosis bronchial cells
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Characterization of bacterial glycolipids in Pediococcus pentosaceus for fermented soybean paste (miso) and Tetragenococcus halophilus for soy sauce, in comparison with those in Lactobacillus, Streptococcus and Staphylococcus species Gram-positive bacterial biomembranes are composed of phosphatidyl glycerol (PG), cardiolipin (CL), and dihexaosyl diglycerides (DH-DG) as the major lipid c

Characterization of bacterial glycolipids in Pediococcus pentosaceus for fermented soybean paste (miso) and Tetragenococcus halophilus for soy sauce, in comparison with those in Lactobacillus, Streptococcus and Staphylococcus species
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Progress in research on DDOST dysregulation in related diseases DDOST is an important subunit of N-glycosylated oligosaccharyltransferase and is closely related to protein N-glycosylation. Some studies have reported tha

Progress in research on DDOST dysregulation in related diseases
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Analysis of site-dependent mucins in rat intestinal mucosa using anti-glycan monoclonal antibodies Intestinal gel-forming mucins are high-molecular weight glycoproteins, and their glycan moieties vary depending on the intestinal site. Although the means

Analysis of site-dependent mucins in rat intestinal mucosa using anti-glycan monoclonal antibodies
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Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments Trypanosoma brucei (T. brucei) parasites cause two major infectious diseases in Africa: African trypanosomiasis in humans (HAT) and Nagana in animals. Desp

Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments
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Lectin-glycan interactions: a comprehensive cataloguing of cancer-associated glycans for biorecognition and bio-alteration: a review This comprehensive review meticulously compiles data on an array of lectins and their interactions with different cancer types through specific glycans. Cr

Lectin-glycan interactions: a comprehensive cataloguing of cancer-associated glycans for biorecognition and bio-alteration: a review
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GM1 oligosaccharide-mediated rescue in GBA-linked Parkinson’s disease via modulation of lysosomal and mitochondrial dysfunctions Mutations in the glucocerebrosidase GBA gene, encoding the lysosomal enzyme β-glucocerebrosidase, represent the most frequent genetic risk factor for

GM1 oligosaccharide-mediated rescue in GBA-linked Parkinson’s disease via modulation of lysosomal and mitochondrial dysfunctions
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Anti-GalNAcα (anti-Tn) antibody repertoire differs between individuals with blood groups A and B Recently, Breiman et al. (2021) reported that the level of anti-Tn in the blood of healthy donors and COVID-19 patients is significantly lower in individua

Anti-GalNAcα (anti-Tn) antibody repertoire differs between individuals with blood groups A and B
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Limited support for a direct connection between prebiotics and intestinal permeability – a systematic review The intestinal barrier is a selective interface between the body´s external and the internal environment. Its layer of epithelial cells is joined toge

Limited support for a direct connection between prebiotics and intestinal permeability – a systematic review
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Association between O-GlcNAc levels and platelet function in obese insulin-resistant subjects Obesity is an epidemic associated with platelet and vascular disorders. Platelet O-GlcNAcylation has been poorly studied in obese subjects. We aimed to eva

Association between O-GlcNAc levels and platelet function in obese insulin-resistant subjects
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Site-directed mutagenesis leads to the optimized transglycosylation activity of endo-beta-N-acetylglucosaminidase from Trypanosoma brucei Endo-β-N-acetylglucosaminidases (ENGases) are pivotal enzymes in the degradation and remodeling of glycoproteins, which catalyze the cleavage or forma

Site-directed mutagenesis leads to the optimized transglycosylation activity of endo-beta-N-acetylglucosaminidase from Trypanosoma brucei
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RACK1 inhibits ferroptosis of cervical cancer by enhancing SLC7A11 core-fucosylation Receiver for Activated C Kinase 1 (RACK1) is a highly conserved scaffold protein that can assemble multiple kinases and proteins together to form complexes

RACK1 inhibits ferroptosis of cervical cancer by enhancing SLC7A11 core-fucosylation
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