Meet our team from April 19-22 at Booth #2017 and learn how the HCR™ platform is empowering real-world cancer research!
We’ll be sharing how researchers use #HCRimaging to get more out of every sample while producing data that stands up to real-world analysis in oncology.
See you at #AACR26!
Discover how the Xenopus pronephros serves as a powerful system for studying nephrogenesis and human kidney disorders, and learn how the Miller Lab uses #HCRimaging to map gene expression across nephron segments!
🗓️ Wednesday, April 1
🕤 8:00 AM PT / 10:00 AM CT
Register today: tinyurl.com/2hxemxss
Is stiffness alone enough to change chemical guidance cues? Embedding soft brain regions in stiff 3D gels incresed levels of chemical guidance cues (using #HCRimaging) compared with soft 3D gels.
Happy Halloween from the MI team! Check out this spooky-themed rat hippocampus image by Jamuna Tandukar using #HCRimaging. 🧠
🟣 Mettl3
⚪️ astrocytes
🟢 nuclei
🟠 rRNA
#onlywithHCR: Colquitt et al. mapped how the loss of auditory feedback destabilizes learned motor behaviors. Using #HCRimaging, they were able to observe the widespread gene expression changes across the birdsong sensorimotor circuit caused by deafening.
🔬Read the full story: tinyurl.com/3fb2hpps
#onlywithHCR: Morales et al. explore the hidden world of bacterial–fungal interactions (BFI). Using #HCRimaging, the team overcame key barriers in detecting endohyphal bacteria and visualized bacterial presence within fungal structures.
Explore the full findings here: tinyurl.com/ya5vpy66
#onlywithHCR: Schember et al. compared the regulatory landscapes of the single-minded (sim) gene in two divergent insects. Using #HCRimaging, their findings highlight the evolutionary rewiring of the gene regulatory network.
Read the full study here: journals.plos.org/plosgenetics...
#onlywithHCR: In a fascinating study, Lopez and Alward used #HCRimaging to visualize cyp19a1 (brain-specific aromatase) mRNA expression in A. burtoni, providing new insight into how androgen signaling may influence social behavior.
Read the full study here: pmc.ncbi.nlm.nih.gov/articles/PMC...
#onlywithHCR: Gray and Lovely leveraged #HCRimaging to fluorescently visualize rar and rxr mRNA in transgenic zebrafish embryos, revealing overlapping expression of multiple rar/rxr genes between 12–32 hours post-fertilization.
Read the full study here: tinyurl.com/5crp99fs
#onlywithHCR: A study by Guillotin et al. reveals how different grass species evolved distinct traits, driven by specialized cell types. #HCRimaging was used to visualize gene expression patterns, uncovering how cell types evolved through gene module recruitment.
Learn more: tinyurl.com/peny8r64
#onlywithHCR: @degrainger.bsky.social, @oliverastone.bsky.social, and their team reveal that lymphatic endothelial cells arise from specialized progenitors. #HCRimaging helped them to visualize endothelial progenitors in whole-mount mouse embryos.
Learn more: www.nature.com/articles/s44...