SNSF Data Portal The Swiss National Science Foundation's Data Portal presents interactive Key Figures, facts on funded projects and involved people in the Grant Search and the COVID-19 project registry, Dataset downlo...

"Experimental Investigations of Human Endogenous Retrovirus Type W (HERV-W) in Relation to Psychiatric and Neurological Disorders"

01.11.2024 – 31.10.2028

Human endogenous retroviruses #HERVs
#MultipleSclerosis, #Schizophrenia

data.snf.ch/grants/grant...

"...We further delineates their pathogenic roles in diseases including #cancer, #autoimmune conditions, and #neurodegenerative disorders. Finally, we discuss emerging strategies targeting #HERVs, including epigenetic modulators,

The roles of human endogenous retrovirus in neurodegenerative diseases: A systematic review Human endogenous retroviruses (HERVs) constitute ∼8 % of the human genome, far exceeding the 2 % occupied by protein-coding genes. Although most HERV …

"The roles of human endogenous retrovirus in neurodegenerative diseases: A systematic review"

#HERVs
#HERV-K
#HERV-W

www.sciencedirect.com/science/arti...

#NewPI #Neuroscience #Immunology #Transposons #SciComm #HERVs

Stay tuned, a few postdoctoral, both molecular and computational biology positions are gonna be advertised soon.

Microbes and Infection | HERV and Diseases | ScienceDirect.com by Elsevier HERV and Diseases

More about #HERVs & diseases

www.sciencedirect.com/special-issu...

Hervcov These are the goals of a project involving researchers from 5 different EU countries. This study has already produced evidence for the induction of a specific protein during COVID-19 disease. New info...

#hervcovproject
#herv #hervs
#longcovid
#postcovid
#retrovirus

Hervcov Project

📣📣 Calling EU-funded Research Projects:

Collaborate with HERVCOV EU project on Long COVID!

Dylan Postmus giving a presentation on his work at the RetroPATH meeting

View from a boat ride on the Neckar River in Tübingen, Germany.

Had an excellent time at this year’s #RetroPATH2025 meeting in Tübingen, Germany, talking about my work on #HIVcure. Many thanks to @agschindler.bsky.social and Daniel Sauter for hosting. Especially interesting was the variety of talks on #HERVs @goffinetlab.bsky.social @lstmnews.bsky.social

Human Endogenous Retroviruses as Novel Therapeutic Targets in Neurodegenerative Disorders Human Endogenous Retroviruses comprise approximately 8% of the human genome, serving as fragments of ancient retroviral infections. Although they are generally maintained in a silenced state by robust...

#HERVs
#Retrovirus

👀👀 #MS #ALS #Alzheimer
#Parkinson #neurodegeneration

pmc.ncbi.nlm.nih.gov/articles/PMC...

Scenic view of Tübingen, Germany: a traditional wooden punt boat with passengers glides along the Neckar River. A punter stands at the rear with a pole. On the riverbank are historic houses with a tower, lush green trees, and flowering plants in the foreground. Picture by Barbara Honner © Verkehrsverein Tübingen

📢 Countdown: 1 month until #Retropath2025!
Registration is still open — join us in Tübingen for outstanding keynote lectures + cutting-edge research on #retroviruses and #HERVs. More info 👉 evis.events/event/469/.

In this introductory episode of the HERVCOV podcast, we explore the fascinating world of human endogenous retroviruses (HERVs) and their unexpected connection to COVID-19 and Long-COVID. Discover how ancient viral fragments hidden in our DNA can influence modern immune responses, the origins of the HERVCOV project, its European collaborators, and its mission to identify biomarkers for personalized treatments. A journey into genomics, cutting-edge research, and the impact of viruses both past and present. Episode Credits Host & Narration Giorgia Burzachechi - Journalist and head of communication and Work Package leader for the communication of the MSCA Night projects ...

#HERVs
#Human Endogenous retrovirus
#HERV-W Env
#Covid19
#LongCovid
#Research
#European Project
#HorizonEU

A stunning first look at the viruses inside us LJI scientists uncover a new avenue for stopping cancers, autoimmune diseases, and more.

"A stunning first look at the viruses inside us"

#HERVs
#HERV-K env

www.lji.org/news-events/...

Promotional banner for RetroPATH 2025, the 34th International Workshop on Retroviral Pathogenesis. The image features colorful historic buildings of Tübingen along the Neckar River at night.

The abstract deadline for #RetroPATH2025 is approaching! Submit by Aug 15 to join the international retrovirology community in Tübingen, Oct 6–9. Details & submission: evis.events/event/469/
#Retroviruses #HERVs

Promotional banner for RetroPATH 2025, the 34th International Workshop on Retroviral Pathogenesis. The image features colorful historic buildings of Tübingen along the Neckar River at night.

The abstract deadline for #RetroPATH2025 is approaching! Submit by Aug 15 to join the international retrovirology community in Tübingen, Oct 6–9. We are excited to be co-organizing this event and hope to see many of you there!
Details & submission: evis.events/event/469/
#Retroviruses #HERVs

A tale of a hidden family of genetic immigrants Though not usual for the editors of a scientific journal to ask that a story be told to its readers, this special issue is offering an opportunity to …

Currently, the study of these endogenous elements and their involvement in certain complex and/or chronic diseases, for which the search for an etiology has often remained based on a monofactorial concept and limited to observable consequences, is being pursued in a broader context of genetic #HERVs

The relationship between HERVs and exogenous viral infections: A focus on the value of HERVs in disease prediction and treatment Human endogenous retroviruses (HERVs) are virus-related sequences that are a normal part of the human genome; they account for about 8% of the human genome. Reactivation of these ancestral proviral...

"The relationship between #HERVs and exogenous viral infections: A focus on the value of HERVs in disease prediction and treatment"

www.tandfonline.com/doi/full/10....

Porträtfoto von Virologin Dr. Michelle Vincendeau vom Helmholtz Munich

Virologin Michelle Vincendeau @m-vincendeau.bsky.social hat uns ein paar Fragen zu ihrer Forschung mit #Organoiden beantwortet und beschreibt, wie sie damit den Einfluss bestimmter Viren auf die Gehirnentwicklung untersucht. 🧠
#HERVs @www.helmholtz-munich.de
👉 www.infectnet.org/web/blog-pos...

Helmholtz Munich Helmholtz Munich, is a member of the Helmholtz Association of German Research Centres

👩‍🔬 Die Münchner Virologin Dr. Michelle Vincendeau @m-vincendeau.bsky.social erforscht mit Gehirn-Organoiden die Rolle von Humanen Endogenen Retroviren ( #HERVs ) bei der Gehirnentwicklung und der Entstehung von neurodegenerativen Erkrankungen. 🧠
👉 www.helmholtz-munich.de/en/viro/rese...

#HERVs
#Retrovirus

Endogenous retroviruses in multiple sclerosis: A network-based etiopathogenic model - PubMed The present perspective article proposes an etiopathological model for multiple sclerosis pathogenesis and progression associated with the activation of human endogenous retroviruses. We reviewed prec...

#MultipleSclerosis

#HERVs
#HERV-W

(PDF) HERV-W Env Induces Neuron Pyroptosis via the NLRP3–CASP1–GSDMD Pathway in Recent-Onset Schizophrenia PDF | HERVs (Human endogenous retroviruses) are remnants of ancient exogenous retroviruses that have integrated into the human genome, particularly in... | Find, read and cite all the research you nee...

FYI @italoromeno.bsky.social.
Already seen this paper?

#HERVs
#HERV-W

Would be interesting to have a specialized researcher’s view about this topic. I’m far more convinced by the role of the #Hervs played, as they are other viruses than EBV that can trigger the HERV-w activation, with the production of the pathogenic envelope protein found in MS brains.

Frontiers | Human endogenous retroviruses and exogenous viral infections

#MultipleSclerosis
#Retrovirus
#HERVs
#HERV-w

FYI @italoromeno.bsky.social 👀

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent co-appear...

HERV (Human Endogenous Retro Viruses) activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity www.biorxiv.org/content/10.1... #MECFS #Fibromyalgia #HERVs

HERVs in children with COVID-19, MIS-C, and KD This study has shown the upregulation of HERVs in children with COVID-19, multisystem inflammatory syndrome (MIS-C), and Kawasaki disease (KD).

#HERVs, inflammatory and regulatory #cytokines are differently expressed in children diagnosed with #COVID-19, #Kawasaki disease, or MIS-C

#multisysteminflammatorysyndromeinchildren

discovermednews.com/hervs-and-cy...

'Dark Genes' Hiding Unseen in Human DNA Have Just Been Revealed Our records of the human genome may still be missing tens of thousands of 'dark' genes.

'Dark Genes' Hiding Unseen in Human DNA Have Just Been Revealed

#HERVs
#DarkGenome

A tale of a hidden family of genetic immigrants Though not usual for the editors of a scientific journal to ask that a story be told to its readers, this special issue is offering an opportunity to …

"A tale of a hidden family of genetic immigrants"

#retrovirus
#HERVs

Fascinating story

Ah non m... zut, spina bifida...
oui, alors les comorbidités on en a, et les maladies auto-immunes aiment bien s'associer à la sep. En même temps si cette histoire de rétrovirus activé est à la base de certaines pathologies, aucune surprise. #HERVs.

Activation of human endogenous retroviruses and its physiological consequences - Nature Reviews Molecular Cell Biology Human endogenous retroviruses (HERVs) are relics of ancient retroviral infections, which provide coding and non-coding sequences to the human genome. Emerging evidence reveals how HERVs contribut...

"Activation of human endogenous retroviruses and its physiological consequences"

#HERVs
#retrovirus

Unveiling the Viral Legacy in our DNA A Journey from Ancient Infections to Modern Mental HealthThe notion that 8% of our genome is derived from ancient viruses sounds like a plot twist from a science fiction movie, but it is true. Hidden ...

#Endogenous #Retrovirus
#HERVs
#Depression
#Schizophrenia
#Bipolar disoorder

"Unveiling the Viral Legacy in our DNA

A Journey from Ancient Infections to Modern Mental Health"

#HERVs