Hydrogen sulfide (H₂S) ameliorates sepsis-induced brain injury by upregulating heme oxygenase-1 (HO-1) to inhibit high-mobility group box 1 (HMGB1) release The incidence of brain injury in sepsis patients has been as high as 70 %, which has been a significant cause of septic patients' death. However, the pathophysiology of brain injury in sepsis is multi...

Hydrogen sulfide (H₂S) protects the brain from sepsis-induced injury by boosting HO-1 and blocking HMGB1. In mice, H₂S improved survival, cognition, and reduced brain damage - a potential therapy for sepsis-related injury.
#Sepsis #Neuroinflam #H2S #HO1 #HMGB1

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