The Power Struggle: Kynurenine Pathway Enzyme Knockouts and Brain Mitochondrial Respiration Kynurenine pathway enzyme knockouts impair mitochondrial respiration. The deletion of kynurenine aminotransferase genes leads to significant impairment of mitochondrial respiration and ATP production...

💥🧬Lose KATs→lose energy!🧠🔥 In kat1-/-, kat2-/- & kat3-/- mice #Cerebellum, #Hhippocampus & #Striatum show crippled #OXPHOS & #ATP drops⚡❗ #Neuroscience #Mitochondria
doi.org/10.1111/jnc....

The Power Struggle: Kynurenine Pathway Enzyme Knockouts and Brain Mitochondrial Respiration Kynurenine pathway enzyme knockouts impair mitochondrial respiration. The deletion of kynurenine aminotransferase genes leads to significant impairment of mitochondrial respiration and ATP production....

💥🧬Lose KATs→lose energy!🧠🔥 In kat1-/-, kat2-/- & kat3-/- mice #Cerebellum, #Hhippocampus & #Striatum show crippled #OXPHOS & #ATP drops⚡❗ #Neuroscience #Mitochondria
doi.org/10.1111/jnc....