Be sure to check out this talk from one of our amazing collaborators! 🧠👩‍🔬

#cerebellum #intervention

How does the cerebellum contribute to cognitive functions? The role of the cerebellum in motor functions is well understood. But why is the same circuitry engaged in functions such as working memory, language, and social cognition? This Unsolved Mystery…

Why is the #cerebellum (known for coordinating motor functions) also engaged in #cognition? @diedrichsenjorn.bsky.social & @actlab.bsky.social investigate the problems that have made it so difficult to answer this question and outline strategies to make progress. 🧪 #NeuroSky

28 THE CENTRAL NERVOUS SYSTEM, BRAIN AND SPINAL CORD EXPLAINED #50LAM_ANATOMY_ENG
youtube.com/shorts/TfCb7...
#centralnervoussystem #brain #spinalcord #cnsanatomy #neuroscience #nervoussystem #cerebrum #cerebellum #brainstem #cerebrospinalfluid

My Niece and Her Neuroscientist - Dr. Roy Sillitoe | Tosh Show Daniel welcomes his niece, who is affected by a rare neurological disorder, and Dr. Roy Sillitoe, a researcher who studies her condition. Support Dr. Roy’s research http://giv.now/csc Support individuals and families affected by Hadley’s condition https://www.pou4f1foundation.org/donate Join our Patreon for exclusive content: http://patreon.com/toshshow Get started today at http://StitchFix.com/tosh to get $20 off your first order—and they’ll waive your styling fee. Text DAN to 64000 to get a FREE pocket pivot and their 10-pattern sprayer with the purchase of ANY size Copper Head hose. Message and data rates may apply Get 25% off your subscription or try the app FREE for seven days at http://Fitbod.me/TOSH http://quince.com/tosh for free shipping on your order and 365-day returns SUBSCRIBE to watch more tosh show https://www.youtube.com/@toshshow TOUR DATES https://www.danieltosh.com/#tour FOLLOW DANIEL TikTok https://www.tiktok.com/@danieltosh Instagram https://www.instagram.com/danieltosh Twitter https://twitter.com/danieltosh ABOUT TOSH SHOW Tosh Show is a window into the mind of comedian Daniel Tosh. Each week, Daniel interviews people from all walks of life that he finds interesting, shares his take on current events, and gives you a little insight into his world. Nothing is off limits, and with endless topics to explore, Tosh and his guests will satisfy everyone's curiosity. Co-Creator/Executive Producer: John Elerick Co-Creator/Executive Producer: Eddie Gossling Co-Creator/Executive Producer: Peter Relyea Audio Engineer: Dylan Stern tosh show https://www.youtube.com/@toshshow Get in touch: toshshow@danieltosh.com

What happens when a neuroscientist sits down with a standup comedian?

Our director joins Tosh Show with Daniel Tosh for a conversation that’s equal parts sharp, surprising, and genuinely funny. #neuroskyence #cerebellum

tinyurl.com/Sillitoe

How does the cerebellum contribute to cognitive functions? The role of the cerebellum in motor functions is well understood. But why is the same circuitry engaged in functions such as working memory, language, and social cognition? This Unsolved Mystery…

Why is the #cerebellum (known for coordinating motor functions) also engaged in #cognition? @diedrichsenjorn.bsky.social & @actlab.bsky.social investigate the problems that have made it so difficult to answer this question and outline strategies to make progress. 🧪 #NeuroSky

How does the cerebellum contribute to cognitive functions? The role of the cerebellum in motor functions is well understood. But why is the same circuitry engaged in functions such as working memory, language, and social cognition? This Unsolved Mystery…

Why is the #cerebellum (known for coordinating motor functions) also engaged in #cognition? @diedrichsenjorn.bsky.social & @actlab.bsky.social investigate the problems that have made it so difficult to answer this question and outline strategies to make progress. 🧪 #NeuroSky

We're Heading to the French Alps for the 𝟵𝘁𝗵 𝗖𝗲𝗿𝗲𝗯𝗲𝗹𝗹𝘂𝗺 𝗗𝗮𝘆𝘀 to join world-leading researchers at the CNRS Paul Langevin Center in 𝗔𝘂𝘀𝘀𝗼𝗶𝘀 from 𝗠𝗮𝗿𝗰𝗵 𝟮𝟲𝘁𝗵 – 𝟮𝟵𝘁𝗵. If you’re interested in exploring the functional activity of your cerebellar slices, be sure to connect with us.
#3Brain #Cerebellum

Did you know our Brain Structure paper model is based on an actual MRI of Dominic's brain? How's that for "keeping it real"! Find out more about this model here: buff.ly/JLjNlWF

#EduSky #brain #nervoussystem #cerebrum #cerebellum #medulla #pituitarygland #hypothalamus #iteachbio

Honored and thrilled to present at JHU's Cerebellum Seminars hosted by the Shadmehr lab-thank you for having me! 🙏 Can cerebellar activity drive a BMI after stroke? Watch here 🧠🎥 www.youtube.com/watch?v=W2be... #BrainMachineInterface #Cerebellum #Neuroscience

La palabra del día de la Real Academia Española. Ejemplo: El cerebelo se ubica en la parte trasera de la cabeza.
#LaPalabraDelDía #cerebelo #latín #cerebellum #NombreMasculino #anatomía

Polystyrene microplastics up-regulates liver glutamine and glutamate synthesis and promotes autophagy-dependent ferroptosis and apoptosis in the cerebellum through the liver-brain axis Microplastics (MPs), which are emerging environmental pollutants, remain uncertainties in their toxic mechanism. MPs have been linked to severe liver …

#ecotoxicology #publichealth #aging #cerebellum #SDGs

Cerebellar Purkinje cells
are harmed by
mixtures of environmental pollutants:

- PM2.5 air pollution,
- methylmercury,
- deltamethrin (insecticide).

Polystyrene microplastics
cause loss of Purkinje cells.
www.sciencedirect.com/science/arti...

Original post on mastodon.social

Radiolab: Song of the #Cerebellum

Episode webpage: https://www.radiolab.org

Media file […]

Superresolved #cerebellum slice stained for Calbindin (🟨Purkinje cells, abberior STAR GREEN, confocal) and for Homer-1 and Bassoon (🟪STAR RED & 🟦STAR ORANGE, STED). Sample courtesy: Abdelali Jalil, Physiologie Cérébrale, French National Centre for Scientific Research, France
#fluorescencefriday

The evolution of gene regulation in mammalian cerebellum development Gene regulatory changes are considered major drivers of evolutionary innovations, including the cerebellum’s expansion during human evolution, yet they remain largely unexplored. In this study, we com...

Outstanding @science.org study on the evolution of gene regulation shaping
#cerebellum development 🧪🧠🧬
@ioansarr.bsky.social @marisepp.bsky.social @tyamadat.bsky.social @steinaerts.bsky.social @kaessmannlab.bsky.social
www.science.org/doi/10.1126/...

Medicine and Pharmacology  -   Neuroscience and Neurology Cerebellar Abnormalities: A Component of Autism Pathophysiology Rekha Jagadapillai, Idil Tuncali, Naveen Nagarajan, Gregory Barnes † and Evelyne Gozal †

For years, the cerebellum was primarily viewed as the center for motor control.

However, a new #preprint reviews the potential role of the cerebellum in Autism spectrum disorder (ASD).

👉 Read the full review: buff.ly/j3LFvu0

#OpenScience #ASD #AutismResearch #Cerebellum #Astroglia #BrainScience

🔥 Hot off Cell Press! 🧠🗣️
Did you know the cerebellum has a language-selective region?
This new fMRI study(n=800+) says so!
👉LangCereb3 is highly language-selective❗
🤔Time to start looking for LangCereb3 aphasias?
Check this out👇
doi.org/10.1016/j.ne...
#Cerebellum
#Aphasia

A Multipannel figure showing FOXP2 expression in developing human Purkinje cells. Panel A: Bulk RNA-sequencing data from BrainSpan showing that FOXP2 is highly expressed in the cerebellum during human brain development. Panel B: Expression of FOXP genes in the developing human cerebellum plotted across timepoints and cell types based on published single-nucleus RNA-sequencing data. Panel C: OXP genes show differential expression across Purkinje cell subtypes, with FOXP1 marking early-born Purkinje cells.

Elizabeth Apsley, Esther Becker & co used CRISPR-based gene editing in cerebellar #organoids to model specific aspects of early human cerebellar development, with a particular focus on the role of the previously understudied FOXP2.

#cerebellum #CRISPR

Read doi.org/10.1242/dmm....

Watercolor paining of a little deer like creature with red antlers. Surreal lowbrow style from evaboneva

"Protect The Cerebellum Cervidae", on view at Haven Gallery. I have have to show her off to the world more :). Look at this widdle babay

Check out the group show here!

havengallery.com/portfolio/li...

#evaboneva #cerebellum #watercolor

Cerebellar deep brain stimulation rescues Purkinje cell mitochondrial density in a genetic mouse model of cerebellar ataxia Deep brain stimulation (DBS) improves motor function in a growing list of movement diseases including Parkinson’s disease, dystonia, and tremor. There…

New exciting findings from @miterkomyerslab.bsky.social (former Sillitoe Lab member): Cerebellar #DBS doesn’t just improve behavior—it remodels Purkinje cells, increasing mitochondrial density and preserving MERCs in a mouse model of cerebellar ataxia. tinyurl.com/DBSMERC #neuroskyence #cerebellum

Integrative behavioral, histological, and proteomics profiling identifies cerebellar drivers of motor dysfunction in a rat model of hepatic encephalopathy.
Acharjee, Arup et al.
Paper
Details
#Cerebellum #HepaticEncephalopathy #Proteomics

Brain-wide mapping of developmental trajectories of cerebellar efferent projections | PNAS Long-range cerebellar outputs are critical for shaping brain-wide functional architecture, influencing motor, cognitive, and affective domains. Pro...

This map pinpoints key windows when cerebellar circuits form, enabling work on how early experiences, genetic variants, or environmental factors shape connectivity and drive neurodevelopmental conditions linked to #cerebellum
Full paper here👇
doi.org/10.1073/pnas...
@csic.es @dicv.csic.es @umh.es

These findings point to the #cerebellum as an early player in brain development, actively contributing to the construction of widespread brain circuits—challenging the traditional view of the cerebellum as a late-maturing structure.

The team reconstructed, for the first time, the step-by-step sequence by which the mouse #cerebellum wires itself to the rest of the brain.
The results reveal that these circuits begin forming much earlier than previously thought, when the cerebellum is still immature 🧠🐭

Long-term impact of digital media on brain development in children - Scientific Reports Scientific Reports - Long-term impact of digital media on brain development in children

When children scroll endlessly on TikTok or similar apps, it matters; our 4-year study found that heavy social-media use was associated with different brain-growth trajectories
#socialmedia #tiktok #cerebellum

www.nature.com/articles/s41...

Our newest research in @pnasnexus.org. In a mouse model for #Williams syndrome, we noticed alterations that the alterations in blood vessels are similar in #heart and #brain. Interestingly, also the #cerebellum showed a different shape of lobule IV/V, related to alterations in the gaiting pattern.

🧠 time 2 study #cerebellum in birdsong? 🧠

In #neuroskyence songbirds are a model to study learned motor skills like speaking a language

The cerebellum plays a role in these behaviors in humans.
It remains unclear if it interacts w/song system, brain areas for song in songbirds

#prattle 💬

1/2

The Power Struggle: Kynurenine Pathway Enzyme Knockouts and Brain Mitochondrial Respiration Kynurenine pathway enzyme knockouts impair mitochondrial respiration. The deletion of kynurenine aminotransferase genes leads to significant impairment of mitochondrial respiration and ATP production...

💥🧬Lose KATs→lose energy!🧠🔥 In kat1-/-, kat2-/- & kat3-/- mice #Cerebellum, #Hhippocampus & #Striatum show crippled #OXPHOS & #ATP drops⚡❗ #Neuroscience #Mitochondria
doi.org/10.1111/jnc....

Check out our latest episode with Dr. @sumrubayin.bsky.social from the @gurdoninstitute.bsky.social!

Learn about her research on neural regeneration in the neonatal mouse #cerebellum. 🧠

A lobule-specific neuronal representation of song temporal structure in the songbird cerebellum The cerebellum is involved in the acquisition and production of speech as revealed by clinical evidence and imaging studies, but its specific role however remains unclear. Songbirds provide a unique m...

Always happy to see researchers like A. Leblois, going beyond the classical birdsong circuit & looking at the #cerebellum to give it its due: “A lobule-specific neuronal representation of song temporal structure in the songbird cerebellum” 🧪🐦🎵🧠
www.biorxiv.org/content/10.1...