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🆕💫The MEFIER Score - A Risk Score to Stratify Infective Endocarditis in Patients with Enterococcus faecalis bacteremia based on an 11-year territory-wide cohort
AUROC of 0.79 (95%CI 0.72-0.88), and a NPV of 0.98 (95%CI 0.97-0.99)
#idsky #IEWiki
academic.oup.com/ofid/advance...

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Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice There is now strong evidence supporting early oral switch (EOS) from intravenous antibiotics in the treatment of infective endocarditis (IE). Our obje…

🆕💫 Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice ESCMID Study Group for Bloodstream Infections, Endocarditis and Sepsis
#idsky #IEWiki
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...

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🆕️⚡️⚡️The largest ever published description of IE outcomes, patients treated in 🇩🇰 after POET had significantly shorter lengths of inpatient hospital stay[-8d]with no change in mortality & an associated lower rate of relapse of bacteremia #IEwiki #idsky #medsky
www.sciencedirect.com/science/arti...

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Combination therapy was not associated with lower rates of in-hospital mortality, "one-mortality" 🤔, IE relapses or persistent bacteraemia. Moreover, it was associated with more frequent adverse reactions, especially acute renal injury. #idsky #IEWiki

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A🆕️🔥 Propensity score analysis of nationwide prospective cohort
Efficacy & safety of Antistaphylococcal penicillin/cefazolin based combination treatment [AG/GENT,VAN, DAP, RIF] Vs monotherapy in patients with MSSA left-sided native valve IE #IEWiki #idsky
www.journalofinfection.com/article/S016...

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