Intravital Multimodal Imaging of Human Cortical Organoids for Chronic Stroke Treatment in Mice
Fu, Janowski, M. et al.
Paper
Details
#HumanCorticalOrganoids #ChronicStrokeResearch #IntravitalImaging

Targeted suppression of glioma by ultralow-dose x-ray–induced photodynamic therapy and gold-based nanoclusters in preclinical models Gold clustoluminogens suppress glioma by ultralow-dose x-ray–induced photodynamic therapy.

Honored and thrilled that my PhD work is selected as the Featured Image on Science Translational Medicine! We developed gold nanoclusters to cross the blood-brain barrier, accumulate in glioblastoma. science.org/doi/10.1126/...
#STM #Glioblastoma #Nanomedicine #Intravitalimaging

Happy #MicroscopyMonday!

Bees didn’t invent the honeycomb—biology’s been doing it at the single-cell level all along.

🟢 GFP-tagged junctions
🔵 Hoechst-stained nuclei

A living mouse intestinal villus.

No blueprint. Just (bio)physics.

#intravitalimaging #biophysics #OME #microscopyenvironment

#MicroscopyMonday | Colon-scoping turned coral reef

Was imaging the colon when I accidentally stumbled into this glowing patch of vascularized white adipose tissue.

🔵 mT/mG mouse (mT-only) → red membranes shown in cyan

Accidental imaging hits different.

#IntravitalImaging #LiveImaging

#IntravitalImaging #PeritubularMicrocirculation #Cisplatin 🐭 #AcuteKidneyInjury
2 mD FITC-dextran DiD-RBC▶️vessel
4 kD TMR-dextran▶️tubule

Microvascular failure precedes renal damage biomarker

CD11b Ab➡️inhibit myeloid cells➡️rescue flow

@jci-insight.bsky.social 2025
insight.jci.org/articles/vie...