Acute Kidney Injury (AKI): Causes, Symptoms & Treatment

AKI is a sudden decline in kidney function that leads to buildup of waste and fluid imbalance in the body. It can develop within hours to days and may be reversible if treated early...
#AcuteKidneyInjury #AKI #Medical #Nursing #iPrkashMishra

Commentary
RNA methylation in acute kidney injury: opening up new therapeutic avenues

doi.org/10.1016/j.kint.2025.12.019

Original article: doi.org/10.1016/j.kint.2025.11.010

#MedSky #NephSky #AKI #acutekidneyinjury

Post-approval data show QUELIMMUNE (SCD-PED), an FDA-approved device for critically ill kids with AKI & sepsis, is safe and effective in real-world use.

Learn more on our science blog: https://ow.ly/G1qb50Yhgjn

#QUELIMMUNE #PediatricNephrology #AcuteKidneyInjury #SepsisCare

Endothelial Prolyl Hydroxylase 3 Mitigates Maladaptive Inflammation to Promote Post-Ischemic Kidney Repair

doi.org/10.1016/j.kint.2026.01.017

#MedSky #NephSky #AKI #acutekidneyinjury @nu-nephrology.bsky.social @feinberg.northwestern.edu

Acute Kidney Injury (AKI): Causes, AEIOU Dialysis, Staging, Complications & Emergency Management
#Medical #Medicine #Nursing #Nurse #AcuteKidneyInjury #nephrology #dialysis #CriticalCare #MedSchool #nursingstudent #internalmedicine #healthcare #hospitallife #VikaasShandily

Nephrology Image
Lateral geniculate body hemorrhage in pediatric hemolytic uremic syndrome

doi.org/10.1016/j.kint.2025.06.024

#MedSky #NephSky #AKI #acutekidneyinjury

Acute Kidney Injury (AKI): Causes, Phases & Nursing Management
#AcuteKidneyInjury #AKI #RenalFailure #PreRenal #VikaasShandily

Scientists report that #selenoprotein GPX3 mitigates #RenalIschemiaReperfusionInjury by suppressing #inflammation via #MAPKPathway inhibition and reduced #NADPH oxidase activity, elevating #IL10 and protecting #kidney tissue. #AcuteKidneyInjury

#OpenAccess: doi.org/10.1016/j.ge...

Acute Kidney Injury (AKI) / Acute Renal Failure (ARF)
#AcuteKidneyInjury #AKI #RenalFailure #Nephrology #VikaasShandily

CD36 drives #ROS-mediated #ferroptosis in #AcuteKidneyInjury by binding and ubiquitinating ferroptosis suppressor protein 1 to promote its degradation, while CD36 loss exacerbates #TubularInjury, highlighting CD36 as a promising AKI #biomarker.

#OpenAccess: doi.org/10.1016/j.ge...

Acute Kidney Injury Associated with Severe Leptospirosis: Fatal Re-Emerging Disease in Latin America
#OpenAccess
Full text 👉 buff.ly/zbXEJsM

#Leptospirosis
#AcuteKidneyInjury
#ZoonoticDisease
#Antibiotics
#PublicHealth
#AKI
#Nephrology
#KidneyCare
#nephsky
#medsky

Commentary
Metabolic heavyweight: thick ascending limb or proximal tubule? Next round
✍️Kevin A Hurtado and Leslie S. Gewin

doi.org/10.1016/j.kint.2025.08.010

Original article: doi.org/10.1016/j.kint.2025.07.021

#MedSky #NephSky @washunephrology.bsky.social #aki #acutekidneyinjury

Commentary
Underappreciated hard worker: resident macrophage patrols and controls local inflammation in kidney
✍️Ryo Yamada and Motoko Yanagita

doi.org/10.1016/j.kint.2025.08.005

Original article: doi.org/10.1016/j.kint.2025.07.022

#NephSky #MedSky #acutekidneyinjury

Cell-type specific single-cell signatures reveal nephrotoxic drug effects. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.012

🔗 Cell-type specific single-cell signatures reveal nephrotoxic drug effects. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#Nephrotoxicity #CellBiology #Cheminformatics #AcuteKidneyInjury #DrugDiscovery #SingleCellGenomics #DrugDevelopment

Kidney ischemia and kidney dysfunction due to mass effect of a retroperitoneal tumor

doi.org/10.1016/j.kint.2025.04.033

#NephSky #MedSky #acutekidneyinjury #aki

JCI Insight - Randomized trial of activated vitamin D for acute kidney injury prevention in critically ill patients

#Medsky🧪 #Immunosky #nephsky #publichealth the study found that treatment with either calcifediol or calcitriol did not significantly reduce #acutekidneyinjury (AKI) in critically ill adults, despite the activated forms of vitamin D upregulating relevant gene pathways.

A20 mitigates oxidized self-DNA–induced #AcuteKidneyInjury by inhibiting STING signaling and #NLRP3-mediated #pyroptosis, with A20-derived peptide P-II offering a therapeutic strategy to improve survival and #renal outcomes. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury - Scientific Reports Scientific Reports - LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury

Using human kidney #organoids, Lin et al. studied sepsis-induced #AcuteKidneyInjury, discovering that a long non-coding RNA improved survival after #LPS exposure—highlighting its regulatory role in sepsis.

www.nature.com/articles/s41...

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Continuous Flow PD Achieves Higher Sodium Removal in Children with AKI | Docwire News Continuous flow peritoneal dialysis achieves greater sodium removal than conventional PD in children with acute kidney injury, mostly due to increased ultrafiltration.

Continuous flow peritoneal dialysis achieved greater sodium removal than conventional PD in children with AKI. #peritonealdialysis #aki #acutekidneyinjury #nephrology #nephsky #pediatrics docwirenews.com/post/continu...

Kidney ischemia and kidney dysfunction due to mass effect of a retroperitoneal tumor

doi.org/10.1016/j.kint.2025.04.033

#NephSky #MedSky #acutekidneyinjury

Dialysis Dependence in AKI Linked to Initiation, Not Timing | Docwire News An analysis showed that the timing of dialysis initiation with acute kidney injury (AKI) did not affect the likelihood of long-term dialysis dependence.

An analysis showed that the timing of #dialysis initiation with #AKI did not affect the likelihood of long-term dependence. #nephrology #nephsky #acutekidneyinjury docwirenews.com/post/dialysi...

Preventing Acute Kidney Injuries How a unique program makes a big difference.

Did you know that 1 in 4 patients sustain an #AcuteKidneyInjury (AKI) in the hospital? With no treatment for AKI, our nephrologists are leading several innovative initiatives to address prevention and management. #NephSky

Kidney-resident macrophages limit toxin-induced inflammation through their hallmark functions

doi.org/10.1016/j.kint.2025.07.022

#NephSky #MedSky #AKI #acutekidneyinjury

Integrated spatial and functional metabolic profiling identified the thick ascending limb as a mitochondrial vulnerability hub in #acutekidneyinjury

doi.org/10.1016/j.kint.2025.07.021

#OpenAccess #NephSky #MedSky #AKI @inserm.fr

Vaccinated Patients With COVID-19 and AKI Fare Better | Docwire News Acute kidney injury (AKI) is common among patients with COVID-19 infections. A study examined their long-term kidney and survival outcomes.

Patients with with COVID-19 and AKI had higher survival and lower odds of staying on CKRT if they were vaccinated against COVID-19. #nephrology #nephsky #acutekidneyinjury #covid #kidneyoutcomes www.docwirenews.com/post/vaccina...

How air pollution can cause kidney disease ‘I will never forget that pain’

“How #airpollution can cause #kidneydisease” — @cenmag.bsky.social
#GlobalHealth #ChronicKidneyDisease #AcuteKidneyInjury

cendigitalmagazine.acs.org/2025/06/23/h...

#KIControversies in Nephrology
Fluid restriction in patients with AKI
You can read the
✅Point
✅Counterpoint
✅Editor's summary
in the July issue of KI
doi.org/10.1016/j.ki...

#MedSky #NephSky #acutekidneyinjury #aki

#Medsky🧪 #IDSky #immunosky #publichealth #Acutekidneyinjury (AKI) is a common complication among unvaccinated & vaccinated patients hospitalised with #COVID. in The study of 972 patients found that

Q fever endocarditis and glomerulonephritis

Q fever diagnosis is challenging: Only a minority of cases present with vegetation or positive blood cultures, making it hard to identify.

doi.org/10.1016/j.kint.2024.12.023

#NephrologyImage #NephSky #MedSky #aki #acutekidneyinjury