Check out my student's posters at the Biophysical Society meeting! Sunday: B110, B111, on the RNA CTD domain, Monday: B112, B114, B115 on ArkA-SH3 binding and B116 on HIV Vif-APOBEC interactions, Tuesday: LB15 on ArkA-SH3 also. #BPS2026 #undergradinthelab #compchem #intrinsicallydisorderedproteins

#KANK1 #LC8 #IntrinsicallyDisorderedProteins #AlphaFold #EM

Attended #BenzonSymposium no. 69 in Copenhagen 🇩🇰 and presented my poster: De novo engineering of functional #IntrinsicallyDisorderedProteins #IDPs 🧪✨

Great insights on protein design, structure prediction & ML in #ProteinScience 🤖🔬

#ProteinDesign #Research

Online now - the Spotlight "Sensitivity to #chirality correlates in a continuum with protein disorder" from Lucia Alvarez and Lucia @chemeslab.bsky.social.

#IntrinsicallyDisorderedProteins #IDPs #steroselectivity

authors.elsevier.com/a/1l18y3S6Gf...

Evaluation of predictions of disordered binding regions in the CAID2 experiment. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.12.009

🧠 How do prediction models perform in recognizing disordered regions with specific binding functions?

🔗 Evaluation of predictions of disordered binding regions in the CAID2 experiment. DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#CAID2 #LigandBinding #IntrinsicallyDisorderedProteins #AI

Original post on mastodon.social

6-Mar-2025
A new algorithm sheds light on ‘disordered’ #proteins

The #IntrinsicallyDisorderedProteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making #structurePrediction particularly challenging. These proteins although exhibit […]

Sequence-Specific Assignments for Intrinsically Disordered Proteins A recent publication in ChemBioChem details how researchers from Italy used NMR spectroscopy to detect proline residues in IDPs. Their NMR spectra were acquired on a Bruker AVANCE NEO spectrometer.

A recent publication in ChemBioChem details how researchers from Italy used NMR spectroscopy to detect proline residues in Intrinsically Disordered Proteins (IDP): goto.bruker.com/40IYWq2

@chemistryeurope.bsky.social

#NMR #Pharma #Pharmaceutical #PharmaIndustry #IntrinsicallyDisorderedProteins

Artistic illustration of a researcher examining an intrinsically disordered protein

Reliable analysis of #IntrinsicallyDisorderedProteins: Researchers of #MainzUniversity and @embl.org Hamburg present new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample 👉 press.uni-mainz.de/reliable-ana... @imbmainz.bsky.social

#IntrinsicallyDisorderedProteins in the center of the pore of the nuclear envelope can form spaghetti-like barrier permeable for cellular factors but blocking viruses and pathogens press.uni-mainz.de/how-wiggly-spaghetti-gua... #biophysics @LemkeLab @imbmainz...