Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use Author(s): Mohammadi, Leila; Navabzadeh, Mina; Jiménez-Téllez, Nerea; Han, Daniel D; Reagan, Emma; Naughton, Jordan; Zhou, Lylybell Y; Almeida, Rahul; Castaneda, Leslie M; Abdelaal, Shadi A; Park, Kat...

Chronic (>1 yr) #Cannabis smoking or THC eating is associated with #EndothelialDysfunction
⏬ #FlowMediatedDilation

#BloodPressure #ArterialStiffness unaffected

N=55 healthy non-tobacco smokers/vapers
29 smokers
9 eaters
26 nonusers

#JAMACardio 2025
jamanetwork.com/journals/jam...

Our study led by A. Flores & with @aniruddhpatelmd.bsky.social describes a new peripheral artery disease PRS. Predictive capability for incident PAD is comparable to CKD & DM2. Among those with PAD, it also associates with major adv limb events jamanetwork.com/journals/jam... @jama.com #JAMACardio

#PolygenicRiskScore for Familial or Sporadic #SpontaneousCoronaryArteryDissection #SCAD
7 SNVs
PHACTR1
LRP1
LINC00310
C1orf51
NOX3
NBEAL1
HSD52
www.nature.com/articles/s41...

Why there are no Fibrillar Collagen variants in this PRS??🫠

#JAMACardio 2024
jamanetwork.com/journals/jam...