Spatial-temporal lipidomics reveals dysregulated lipid metabolism in mouse brain during Alzheimer’s disease progression Tracking spatial lipidomic changes during Alzheimer’s disease (AD) progression is crucial for elucidating the underlying mechanisms of the disease.Thi…

Spatial-temporal lipidomics reveals dysregulated lipid metabolism in mouse brain during Alzheimer’s disease progression #JAdvRes #MassSpec www.sciencedirect.com/science/arti...

Drug-resistant Escherichia coli metabolomics via pseudo-targeted SWATH/IDA-MRM: Bridging high coverage and precision Metabolic reprogramming plays a significant role in the emergence, progression, and response to antibiotic pressure in bacterial resistance. Current m…

Drug-resistant Escherichia coli metabolomics via pseudo-targeted SWATH/IDA-MRM: Bridging high coverage and precision #JAdvRes www.sciencedirect.com/science/arti...

Proteomic profiling in cerebrospinal fluid reveal biomarkers for shunt outcome in idiopathic normal-pressure hydrocephalus The pathophysiology of idiopathic normal pressure hydrocephalus (iNPH) remains unclear, and the treatment strategy remains suboptimal. This study aims…

Proteomic profiling in cerebrospinal fluid reveal biomarkers for shunt outcome in idiopathic normal-pressure hydrocephalus #JAdvRes #MassSpec www.sciencedirect.com/science/arti...

Monocyte➡️ #SmoothMuscleCell #EndothelialCell phenotypic shift in #AorticDissection

Lyz2-CreERT2:Basp1 f/f or AAV8-shBasp1🐭+BAPN
👉abrogate thoracic aortic dilation
👉50~80%⏬ #AorticDissection Mortality

In vitro BASP1+ monocyte
⏫ SMC EC Apoptosis

#JAdvRes 2025
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Screening, identification and detection of the regulated and emerging mycotoxins in edible and medicinal products by integrating diversiform liquid chromatography/mass spectrometry systems and high-th... Safety issues pertaining to mycotoxin contamination of the edible and medicinal products (EMPs) have attracted significant attention. EMPs not only ha…

Screening, identification and detection of the regulated and emerging mycotoxins in edible and medicinal products by integrating diversiform liquid chromatography/mass spectrometry systems and high-throughput sequencing of contaminated fungi #JAdvRes www.sciencedirect.com/science/arti...