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Drug Interactions With Excessive Daytime Sleepiness Treatments - Stanley V. Thomas, Mark A. Malesker, Daniel E. Hilleman, Naresh A. Dewan, 2025 Objective: To evaluate the potential for drug interactions with pharmacotherapy for central hypersomnolence (modafinil, armodafinil, solriamfetol, pitolisant, s...

#OnlineFirst w/ #PMT #JPharmTechnol this week, Thomas et al w/Creighton University reviewed the potential for toxicity-causing drug interactions and adverse reactions w/use of hypersomnolence treatments, often via CYP enzyme pathway
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PMC12496447
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#OnlineFirst w/ #PMT #JPharmTechnol this week, Hammaker et al w/Atrium Health NC compare outcomes of acute ischemic stroke treated with tenecteplase versus first-line alteplase
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On PubMed at PMC12491217
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Extending Universal Licensing Recognition (ULR) Laws to Licensure Renewal: A Pharmacist Case Study - Alex Adams, Edward J. Timmons, 2025 Universal Licensing Recognition (ULR) laws have emerged as a key policy tool to improve license mobility by allowing licensure obtained in one state to be more ...

#OnlineFirst w/ #PMT #JPharmTechnol Adams&Timmons discuss universal licensing recognition reforms + Hensler&Burghardt report that apixaban concentrations are maintained during therapeutic plasma exchange

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#OnlineFirst w/ #PMT #JPharmTechnol - Sigala et al found in chart review that use of oral factor Xa inhibitors concentrations to guide anticoagulation transition in the ICU did not impact major bleeding events or thromboembolic complications.
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#OnlineFirst w/ #PMT #JPharmTechnol today, issue 41(6) features #vancomycin use---MRSA PCR pneumonia testing, dose modeling, & AKI---& covers benefits of pharmacist consult service for warfarin mgmt, refeeding syndrome, + peritonitis w/ #PPI use
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journals.sagepub.com/toc/pmta/41/6

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#OnlineFirst w/ #PMT #JPharmTechnol this week, Sunshine & colleagues at Henry Ford Health in Detroit demonstrated that an interruptive EHR alert significantly improved guideline-appropriate prescribing of metronidazole to treat trichomoniasis.
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#OnlineFirst w/ #PMT #JPharmTechnol this week, Cabanilla and colleagues with New Mexico Health Sciences Center report clinical outcomes of 3 hospitalized patients with Legionella pneumonia who received doxycycline monotherapy
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PMID: PMC12399582

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Proton Pump Inhibitor Use in Patients With Cirrhosis and Its Association With Spontaneous Bacterial Peritonitis - Morgan Thomas, Cameron Lanier, Kelly Covert, 2025 Background: Cirrhosis is a major cause of morbidity and mortality in the United States, with spontaneous bacterial peritonitis (SBP) being a serious complicatio...

#OnlineFirst w/ #PMT #JPharmTechnol this week, Thomas et al w/E Tenn State Univ assess use of proton pump inhibitors in outpatients w/cirrhosis, finding frequent undocumented use & potential overuse of PPIs.
Free Full-Text: PMC12373648
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#OnlineFirst w/ #PMT #JPharmTechnol this week, Hoke and colleagues at North Florida/South Georgia Veterans Health System assess rates of refeeding syndrome in patients w/ or w/o IV electrolyte supplementation before parenteral nutrition

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Evaluating the Effectiveness of a Pharmacist-Driven Warfarin Consult Service Versus Physician Management in a Tertiary Community Hospital - Erik Wasowski, Anne Harris, Taylor Elias, 2025 Background: The use of warfarin is complicated by a narrow therapeutic window, requiring close monitoring to prevent serious adverse events. Literature has show...

#OnlineFirst w/ #PMT #JPharmTechnol this week, Wasowski & colleagues w/ Cleveland Clinic found lower starting doses and fewer INRs >/= 0.7 when a pharmacist-driven #warfarin consult service was implemented, vs physician care

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free PMCID: PMC12343540
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#OnlineFirst w/ #PMT #JPharmTechnol - Mulageta et al found significantly lower #vancomycin levels + shorter txt w/o negative outcomes using PCR-based (vs culture) MRSA nasal screening in hospitalized patients w/pneumonia
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Free PMC: PMC12328358

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#OnlineFirst w/ #PMT #JPharmTechnol this week - Li & colleagues identify higher risk of acute kidney injury in critically ill using vancomycin + piperacillin-tazobactam vs monotherapy + other beta-lactams
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Available as free PMC on PubMed
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#OnlineFirst w/ #PMT #JPharmTechnol this week - Burroughs & colleagues found in a nationwide survey of pharmacists at transplant centers that anticoagulant selection and effects in patients prescribed azoles varied widely

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Ensifentrine: A Novel Option for Maintenance of Chronic Obstructive Pulmonary Disease - Emily M. Hitt, Alexa J. Powell, 2025 Objective: The goals of this article are reviewing the clinical aspects of ensifentrine, results from the clinical trials that led to its approval and examining...

#OnlineFirst w/ #PMT #JPharmTechnol this week - Hitt & Powell w/ Washington State Univ College of Pharmacy and Pharm Sci review ensifentrine as a new adjunct for patients with #COPD experiencing symptoms w/existing treatment options
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Vamorolone Versus Traditional Glucocorticoids in Duchenne Muscular Dystrophy: A Review and Meta-Analysis of Efficacy and Safety - Dawood Javed, Abdullah Javed, Faran Ahmed Jajja, Ahmed Jahanzeb, 2025 Objective: This meta-analysis evaluates the efficacy and safety of vamorolone, a dissociative glucocorticoid, compared with traditional glucocorticoids in treat...

#OnlineFirst w/ #PMT #JPharmTechnol this week - Javed and colleagues in Pakistan assess vamorolone for Duchenne muscular dystrophy and find it effective and safer than traditional glucocorticoids for growth and bone health

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Correlation of HbA1c and Continuous Glucose Monitor Time in Range - Hannah DePasquale, Alexander DeLucenay, Nabila Ahmed-Sarwar, 2025 Background: Current literature is limited to describing the correlation of continuous glucose monitor (CGM) use and improved HbA1cs in patients with type 2 diab...

#OnlineFirst w/ #PMT #JPharmTechnol - DePasquale & colleagues at Rochester Regional Health correlated lower HbA1c w/more time in range in adults w/diabetes using continuous glucose monitors w/clinic care by a pharmacist and nurse practitioner
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Emergency Drug Box Accuracy: Analysis of Manual Replenishment Errors and the Use of RFID as a Preventative Strategy - Mohamed Sarg, Megan Rowcliffe, Agnes Ann Feemster, E. Robert Feroli, Rosemary Dunc... Background: Emergency drug boxes (EDBs) contain essential medications and supplies for use during life-threatening emergencies. Most health system pharmacies us...

#OnlineFirst w/ #PMT #JPharmTechnol this week, Sarg & colleagues in east coast med centers examined emergency medicine boxes for accuracy, finding errors in 24%, and estimated error reduction of <70% w/radio frequency identification technology

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#OnlineFirst w/ #PMT #JPharmTechnol this week - Jagadish and colleagues w/East Tennessee State Univ report a case of pleural effusion and anasarca potentially connected with pioglitazone administration
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#OnlineFirst w/ #PMT #JPharmTechnol this week, and #openaccess - van der Hoeven & colleagues w/Univ Texas Health Sci Center compare microbial contamination of propofol in different drug disposal devices
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#OnlineFirst w/ #PMT #JPharmTechnol - Phillips & colleagues w/Univ Florida Coll Pharmacy used computer simulations to build pharmacy student understanding of and empathy toward patients with common healthcare issues in ambulatory care settings

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#OnlineFirst w/ #PMT #JPharmTechnol this week, Smith & colleagues report similar outcomes when #ambulatorycare #pharmacists offer post-COVID drug therapy management to patients with #diabetes in person or online
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Thiamine and Ascorbic Acid in Sepsis and Septic Shock: A Review of Evidence for their Role in Practice - Justin P. Reinert, Kegan Becker, Martin J. Ohlinger, 2025 Objective To evaluate the evidence for the use of ascorbic acid, thiamine, or a combination of both agents without corticosteroids in the management of sepsis a...

#OnlineFirst w/ #PMT #JPharmTechnol this week, Reinert & colleagues w/Univ Toledo COP evaluate ascorbic acid, thiamine, or a combination of both agents without corticosteroids to manage sepsis/septic shock

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Optimizing the Dosing of Heparin for Therapeutic Anticoagulation in Neurocritical Care Patients at High Risk of Bleeding: Report on a Quality Improvement Initiative - Sahil Kapoor, Nick Scaturo, Garre... Background: Heparin infusions are used to treat and prevent thromboembolic complications in neurocritical care, but optimal dosing in patients with acute intrac...

#OnlineFirst w/ #PMT #JPharmTechnol this week, Kapoor and colleagues w/Wake Forest Baptist Health report reduced time to reach therapeutic target of heparin from a quality improvement initiative in neurocritical care patients
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Journal of Pharmacy Technology - Volume 41, Number 3 Table of contents for Journal of Pharmacy Technology, 41, 3

#OnlineFirst w/ #PMT #JPharmTechnol this week, issue 41(3) covers adversedrugreactions , DOAC dosing strategies and safety, first-in-class treatment for PAH, implants for ocular hypertension and glaucoma, & comments on naloxone instruction

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#OnlineFirst w/ #PMT #JPharmTechnol this week, Ho et al w/California Poison Control System report increased calls to poison centers + hospital utilization w/exposure to glucagon-like peptide-1 receptor agonists for weight management
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#FromtheArchives of #PMT #JPharmTechnol this week, Okraszewski et al w/ Cleveland Clinic in 2019, comparing #pharmacist vs physician management of refill requests, found better #medicationmanagement and quality of care by RPhs than by physicians
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#OnlineFirst w/ #PMT #JPharmTechnol this week, Martinez-Orea & colleagues in Spain report cost and adherence concerns as barriers to intramuscular antiretroviral therapy
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Salvage Therapy With a Triple Combination of Daptomycin, Carbapenem, and Oxazolidinone in Patients With Persistent MRSA Bacteremia of Cardiovascular Focus: A Case Series - Kotaro Mitsutake, Natsuki Sh...

#OnlineFirst w/ #PMT #JPharmTechnol this week, Mitsutake & colleagues explore salvage therapy options for persistent #MRSA bacteremia

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#OnlineFirst w/ #PMT #JPharmTechnol this week, Phyo et al at Eskanazi Health in Indianapolis find that fixed dosing of prophylactic enoxaparin may be insufficient in patients w/BMI of 40 kg/m2 or greater:
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#anticoagulation #medicationmanagement #PharmSky #MedSky

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#OnlineFirst w/ #PMT #JPharmTechnol this week, Datta & colleagues w/the UConn School of Pharmacy comment on the appropriateness of naloxone instructions in cases of #overdose of adulterated opioids and suggest needed updates
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#substanceabuse
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