#OnlineFirst w/ #PMT #JPharmTechnol this week, Thomas et al w/Creighton University reviewed the potential for toxicity-causing drug interactions and adverse reactions w/use of hypersomnolence treatments, often via CYP enzyme pathway
journals.sagepub.com/doi/abs/10.1...
PMC12496447
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Hammaker et al w/Atrium Health NC compare outcomes of acute ischemic stroke treated with tenecteplase versus first-line alteplase
#PharmSky #MedSky
On PubMed at PMC12491217
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol Adams&Timmons discuss universal licensing recognition reforms + Hensler&Burghardt report that apixaban concentrations are maintained during therapeutic plasma exchange
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and
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#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol - Sigala et al found in chart review that use of oral factor Xa inhibitors concentrations to guide anticoagulation transition in the ICU did not impact major bleeding events or thromboembolic complications.
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol today, issue 41(6) features #vancomycin use---MRSA PCR pneumonia testing, dose modeling, & AKI---& covers benefits of pharmacist consult service for warfarin mgmt, refeeding syndrome, + peritonitis w/ #PPI use
#PharmSky #MedSky
journals.sagepub.com/toc/pmta/41/6
#OnlineFirst w/ #PMT #JPharmTechnol this week, Sunshine & colleagues at Henry Ford Health in Detroit demonstrated that an interruptive EHR alert significantly improved guideline-appropriate prescribing of metronidazole to treat trichomoniasis.
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol this week, Cabanilla and colleagues with New Mexico Health Sciences Center report clinical outcomes of 3 hospitalized patients with Legionella pneumonia who received doxycycline monotherapy
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
PMID: PMC12399582
#OnlineFirst w/ #PMT #JPharmTechnol this week, Thomas et al w/E Tenn State Univ assess use of proton pump inhibitors in outpatients w/cirrhosis, finding frequent undocumented use & potential overuse of PPIs.
Free Full-Text: PMC12373648
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol this week, Hoke and colleagues at North Florida/South Georgia Veterans Health System assess rates of refeeding syndrome in patients w/ or w/o IV electrolyte supplementation before parenteral nutrition
journals.sagepub.com/doi/abs/10.1...
#MedSky #PharmSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Wasowski & colleagues w/ Cleveland Clinic found lower starting doses and fewer INRs >/= 0.7 when a pharmacist-driven #warfarin consult service was implemented, vs physician care
journals.sagepub.com/doi/abs/10.1...
free PMCID: PMC12343540
#PharmSky
#OnlineFirst w/ #PMT #JPharmTechnol - Mulageta et al found significantly lower #vancomycin levels + shorter txt w/o negative outcomes using PCR-based (vs culture) MRSA nasal screening in hospitalized patients w/pneumonia
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
Free PMC: PMC12328358
#OnlineFirst w/ #PMT #JPharmTechnol this week - Li & colleagues identify higher risk of acute kidney injury in critically ill using vancomycin + piperacillin-tazobactam vs monotherapy + other beta-lactams
journals.sagepub.com/doi/abs/10.1...
Available as free PMC on PubMed
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week - Burroughs & colleagues found in a nationwide survey of pharmacists at transplant centers that anticoagulant selection and effects in patients prescribed azoles varied widely
journals.sagepub.com/doi/abs/10.1...
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week - Hitt & Powell w/ Washington State Univ College of Pharmacy and Pharm Sci review ensifentrine as a new adjunct for patients with #COPD experiencing symptoms w/existing treatment options
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol this week - Javed and colleagues in Pakistan assess vamorolone for Duchenne muscular dystrophy and find it effective and safer than traditional glucocorticoids for growth and bone health
journals.sagepub.com/doi/abs/10.1...
#PharmSky #MedSky #raredisease
#OnlineFirst w/ #PMT #JPharmTechnol - DePasquale & colleagues at Rochester Regional Health correlated lower HbA1c w/more time in range in adults w/diabetes using continuous glucose monitors w/clinic care by a pharmacist and nurse practitioner
journals.sagepub.com/doi/abs/10.1...
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Sarg & colleagues in east coast med centers examined emergency medicine boxes for accuracy, finding errors in 24%, and estimated error reduction of <70% w/radio frequency identification technology
journals.sagepub.com/doi/abs/10.1...
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week - Jagadish and colleagues w/East Tennessee State Univ report a case of pleural effusion and anasarca potentially connected with pioglitazone administration
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol this week, and #openaccess - van der Hoeven & colleagues w/Univ Texas Health Sci Center compare microbial contamination of propofol in different drug disposal devices
#PharmSky #MedSky
journals.sagepub.com/doi/full/10....
#OnlineFirst w/ #PMT #JPharmTechnol - Phillips & colleagues w/Univ Florida Coll Pharmacy used computer simulations to build pharmacy student understanding of and empathy toward patients with common healthcare issues in ambulatory care settings
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#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Smith & colleagues report similar outcomes when #ambulatorycare #pharmacists offer post-COVID drug therapy management to patients with #diabetes in person or online
journals.sagepub.com/doi/abs/10.1...
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Reinert & colleagues w/Univ Toledo COP evaluate ascorbic acid, thiamine, or a combination of both agents without corticosteroids to manage sepsis/septic shock
journals.sagepub.com/doi/abs/10.1...
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Kapoor and colleagues w/Wake Forest Baptist Health report reduced time to reach therapeutic target of heparin from a quality improvement initiative in neurocritical care patients
journals.sagepub.com/doi/abs/10.1...
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, issue 41(3) covers adversedrugreactions , DOAC dosing strategies and safety, first-in-class treatment for PAH, implants for ocular hypertension and glaucoma, & comments on naloxone instruction
journals.sagepub.com/toc/pmta/41/3
#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Ho et al w/California Poison Control System report increased calls to poison centers + hospital utilization w/exposure to glucagon-like peptide-1 receptor agonists for weight management
#openaccess #PharmSky #MedSky
journals.sagepub.com/doi/full/10....
#FromtheArchives of #PMT #JPharmTechnol this week, Okraszewski et al w/ Cleveland Clinic in 2019, comparing #pharmacist vs physician management of refill requests, found better #medicationmanagement and quality of care by RPhs than by physicians
#PharmSky #MedSky
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol this week, Martinez-Orea & colleagues in Spain report cost and adherence concerns as barriers to intramuscular antiretroviral therapy
#MedSky #PharmSky
journals.sagepub.com/doi/abs/10.1...
#OnlineFirst w/ #PMT #JPharmTechnol this week, Mitsutake & colleagues explore salvage therapy options for persistent #MRSA bacteremia
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#PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Phyo et al at Eskanazi Health in Indianapolis find that fixed dosing of prophylactic enoxaparin may be insufficient in patients w/BMI of 40 kg/m2 or greater:
journals.sagepub.com/doi/abs/10.1...
#anticoagulation #medicationmanagement #PharmSky #MedSky
#OnlineFirst w/ #PMT #JPharmTechnol this week, Datta & colleagues w/the UConn School of Pharmacy comment on the appropriateness of naloxone instructions in cases of #overdose of adulterated opioids and suggest needed updates
journals.sagepub.com/doi/abs/10.1...
#substanceabuse
#MedSky
#PharmSky