Blocking Integrin αV (Cilengitide or SB273005) aggravates ascending aortic aneurysm & dissection in 🐭+BAPN

Transcriptional role of STAT1 on SMC contractile proteins

Integrins αV αL ⬇️in👤type A #AorticDissection

Plasma #Proteomics 11 case + 7 ctrl

#JTCVS 2025
www.sciencedirect.com/science/arti...

A nomogram of pre-operative predictors for Persistent Paraplegia in #ThoracoAbdominalAorticAneurysm repair
#AortaEd

N=2827
Persistent Paraplegia 68
Persistent Paraparesis 55
Transient SCD 132

Diabetes
prior PCI
CKD
🚬
Symptomatic aorta
Crowford extent

#JTCVS 2025
www.jtcvs.org/article/S002...

The effect of donor distance on post-transplant mortality in the modern era In the new US heart transplant allocation system, eligible patients can receive hearts from donors beyond a 250-mile radius. The safety of extended tr…

Congratulations to Dr. Atluri and his lab for their recent publication in #JTCVS Open focused on understanding the impact distances between donor and transplant centers have on post-transplant outcomes.
bit.ly/4lvtyDN

My continued biomedical education

Personalized external aortic root support (PEARS)
Stabilizing, instead of replacing, the dilating aortic root

An inspiring journey from Clinician-Patient mind to Operation room

Can we load drugs on this Dacron mesh? 😆

#JTCVS 2024
www.jtcvs.org/article/S002...

#AorticValve Cusp Morphometry in dilated trileaflet Aortic Roots
104 case (root ≥45 mm) + 146 Ctrl (< 40 mm)
73 Propensity score-matched pairs

Cusp insertion length & free margin length increase as root dilates

#AortaEd
#JTCVS 2024
www.sciencedirect.com/science/arti...

Use alternate aortic size indice, instead of aortic diameter, for surgical eligibility of patients with moderate #AscendingAorticAneurysm (aortic Diam 5.0~5.4 cm)

♀️ are ~3 times more likely to reach threshold size than♂️
#TitanSvS registry
#AortaEd
#JTCVS 2024
www.sciencedirect.com/science/arti...

3 decades (1996-2023) experience on Long-term outcomes of recurrent type A/B #AorticDissection

326/316 matched pairs
Recurrent vs Initial AD
3 yr f/up

Survival
R ~ I
Major Aortic Events
A: R > I; B: R ~ I
Extension of Dissection
R > I

#AortaEd
#JTCVS 2024
www.sciencedirect.com/science/arti...

Distal Aortic events in #MarfanSyndrome
N=124, 11 yr f/up

Type B #AorticDissection
#AorticAneurysm
Re-intervention
Mortality

"Pre-operative hypertension (OR 3.96, p=0.012) increased the risk of TBAD"

#AortaEd
Arjune Dhanekula lab #JTCVS 2023
www.sciencedirect.com/science/arti...