Sex-specific Mortality after Surgery for Acute Type A #AorticDissection
#AortaEd

327♀️+ 551♂️

30-d/In-hosp mortality ♀️20.5% vs ♂️18.5%

Long-term (6.2 y f/up) mortality ♀️4.1% vs ♂️2.6% per patient-year over 10 y
♀️Age COPD CKD #AorticAneurysm
♂️Age MI

#JTCVSOpen 2025
www.jtcvsopen.org/article/S266...

Outcomes after open repair of aortic aneurysms & dissections in #Cannabis🌿 consumers vs non-users
N=134

Mortality↔️
Intra-op events ↔️
Respiratory complications⬆️
Post-op stroke⬆️
AKI⬆️

Cannabis users use other drugs more frequently

#AortaEd
#JTCVSOpen 2024
www.sciencedirect.com/science/arti...

Personalized (🐷) 3D-printed PCL-PLGA hemiarch-descending thoracic aortic graft

Computational fluid dynamics simulation to optimize shear & flow

3-mo implants
No aneurysm
Re-endothelialized but hypermuscularized

#AortaEd
Narutoshi Hibino lab #JTCVSOpen 2024
www.sciencedirect.com/science/arti...

Patient-specific #ThoracicAorticAneurysm failure risk (ratio::Max in vivo wall stress/wall strength) at Axial direction has a stronger correlation with in vivo distensibility coefficient than morphometrics (diameter, length, volume)

#AortaEd

#JTCVSOpen 2024
www.jtcvsopen.org/article/S266...

Regionalized #Mechanobiology of👤#AscendingAorticAneurysm

Aneurysmal Ascending Aorta
⏫#EnergyLoss #ElasticityModulus
⏬#DelaminationStrength

Aneurysmal Aortic Root
Unaltered #EnergyLoss #ElasticityModulus
⏬#DelaminationStrength

#AortaED

#JTCVSOpen 2024
www.jtcvsopen.org/article/S266...