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#
Hashtag
#KZFP
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Our work therefore identifies a #KZFP that regulates #enhancer function through targeting domesticated #transposon sequences and operates in a #heterochromatin independent manner.

It also suggests a molecular mechanisms that may underlie the genetic association between ZKSCAN3 and #schizophrenia.

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In this work, Daniel genetically targeted mouse embryonic stem cells to knock in degron and epitope tags to the endogenous Zkscan3 locus. This allowed him to manipulate and track this enigmatic #KZFP to understand its genomic localisation, function and molecular mechanism of action.

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