Preclinical Toxicology Supply for a Complex API Enabled by Asymmetric Catalysis and Rapid Chemical Development: IL-17A Inhibitor LY3509754 The chemical development and production of sufficient amounts of IL-17A inhibitor LY3509754 to enable preclinical toxicology studies is described. LY3509754 is a complex small molecule that features t...

#ChemSky Super #OPRD out today from #LillyChem on an IL17 compound from discovery to process chem. A ln extensive look at all the chemistry needed to bring this complex API to key preclinical studies
A great read!