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Triplet Versus Doublet Chemotherapy Before Hepatectomy in Colorectal Liver Metastases: Results from a Multicenter Study - OncoDaily Triplet chemo (FOLFOXIRI) before liver resection is safe and may improve survival in colorectal liver metastases, especially in high TB cases.

Triplet Versus Doublet Chemotherapy Before Hepatectomy in Colorectal Liver Metastases: Results from a Multicenter Study

oncodaily.com/trial-update...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #CRC #CLM #Hepatectomy #LiverMetastases

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Novel tRNA fragments enable prognosis for liver metastases for the first time Read more!

tRNA fragments as reliable #biomarkers for #livermetastases of #coloncancer?

Researchers at #CCCVienna of #MedUniVienna have succeeded for the first time in identifying #tRNA fragments that can reliably predict which patients have a favourable or unfavourable prognosis. ⬇️

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💫HPB Journal Highlight 💫 📢 New AHPBA Guidelines! For colorectal liver metastases: MRI is preferred, PET for extra-hepatic disease, and upfront surgery over chemo for resectable cases. Surgeons play a key role! 🔬 🔗https://tinyurl.com/yknj83jj
#ColorectalCancer #LiverMetastases

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Colorectal liver oligometastases (CLOM) patients with right-sided primary CRC have worse survival post-ablation. The reported MRSL score helps identify high-risk CLOM patients who may benefit from additional treatments. #ColorectalCancer #LiverMetastases #PrecisionMedicine

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In a phase III trial, thermal ablation was found to be noninferior to surgical resection for overall survival in patients with small resectable colorectal liver metastases. The thermal ablation group also had a better safety profile. ascopost.com/news/februar... #LiverMetastases #ColorectalCancer

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February Issue: CEA Rebound After Discontinuation of Pre-Hepatectomy Chemotherapy Predicts Worse Outcomes After Resection of #ColorectalCancer #LiverMetastases

rdcu.be/eaONj

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Öcal et al. show that #SIRT induces local #immune effects in untreated microsatellite stable #CRC #LiverMetastases and systemic exhaustion of #immune cells in non-responders. Synergism of #SIRT and checkpoint inhibition warrant further investigation.

t.co/WujHzfCq7Z

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Identification and Verification of Key Genes in Colorectal Cancer Liver Metastases Through Analysis of Single-Cell Sequencing Data and TCGA Data

Annals of Surgical Oncology repost:

December Issue: Identification and Verification of Key Genes in #ColorectalCancer #LiverMetastases Through Analysis of Single-Cell Sequencing Data and TCGA Data

rdcu.be/d1TeM

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