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Morphological and Hyperphosphorylation Transitions of Nanoscale Tau Aggregates in Alzheimer's Disease Super-resolution microscopy identifies nano-sized tau aggregates (nano-aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age-Relate...

๐—ง๐—ฎ๐˜‚ ๐—ป๐—ฎ๐—ป๐—ผ-๐—ฎ๐—ด๐—ด๐—ฟ๐—ฒ๐—ด๐—ฎ๐˜๐—ฒ ๐˜๐—ฟ๐—ฎ๐—ป๐˜€๐—ถ๐˜๐—ถ๐—ผ๐—ป๐˜€ ๐—ถ๐—ป ๐—”๐—น๐˜‡๐—ต๐—ฒ๐—ถ๐—บ๐—ฒ๐—ฟ'๐˜€ ๐——๐—ถ๐˜€๐—ฒ๐—ฎ๐˜€๐—ฒ ๐—ฟ๐—ฒ๐˜ƒ๐—ฒ๐—ฎ๐—น๐—ฒ๐—ฑ ๐—ฏ๐˜† ๐——๐—ก๐—”-๐—ฃ๐—”๐—œ๐—ก๐—ง

Full study: doi.org/10.1002/advs...

Authors used our anti-mouse and anti-rabbit DNA-PAINT kits for tau visualization in brain tissue sections.

Congratulations to all authors!!

#DNAPAINT #SMLM #MassivePhotonics

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๐Ÿš€ ๐—œ๐—ป๐˜๐—ฟ๐—ผ๐—ฑ๐˜‚๐—ฐ๐—ถ๐—ป๐—ด ๐— ๐—”๐—ฆ๐—ฆ๐—œ๐—ฉ๐—˜-๐—ฅ๐—ก๐—”-๐—™๐—œ๐—ฆ๐—› ๐—ฃ๐—ฟ๐—ผ๐—ฏ๐—ฒ๐˜€ ๐—ฎ๐—ป๐—ฑ ๐—•๐˜‚๐—ณ๐—ณ๐—ฒ๐—ฟ ๐—ž๐—ถ๐˜๐˜€ ๐—ถ๐—บ๐—ฎ๐—ด๐—ถ๐—ป๐—ด of RNA targets ๐˜‚๐˜€๐—ถ๐—ป๐—ด ๐——๐—ก๐—”-๐—ฃ๐—”๐—œ๐—ก๐—ง ๐—บ๐—ถ๐—ฐ๐—ฟ๐—ผ๐˜€๐—ฐ๐—ผ๐—ฝ๐˜†.
๐Ÿ”—: www.massive-photonics.com/product-cate...

#SMLM #DNAPAINT #RNAImaging #RNAFISH #Microscopy #MassivePhotonics

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Preview
3D MINFLUX combined with DNA-PAINT resolves the arrangement of Bassoon at active zones Neurotransmitter release and membrane retrieval at active zones require precise spatial and temporal coordination relying on an intricate molecular machinery. However, the exact nano-structural organi...

New pre-print alert! โ€œ๐Ÿฏ๐—— ๐— ๐—œ๐—ก๐—™๐—Ÿ๐—จ๐—ซ ๐—ฐ๐—ผ๐—บ๐—ฏ๐—ถ๐—ป๐—ฒ๐—ฑ ๐˜„๐—ถ๐˜๐—ต ๐——๐—ก๐—”-๐—ฃ๐—”๐—œ๐—ก๐—ง ๐—ฟ๐—ฒ๐˜€๐—ผ๐—น๐˜ƒ๐—ฒ๐˜€ ๐˜๐—ต๐—ฒ ๐—ฎ๐—ฟ๐—ฟ๐—ฎ๐—ป๐—ด๐—ฒ๐—บ๐—ฒ๐—ป๐˜ ๐—ผ๐—ณ ๐—•๐—ฎ๐˜€๐˜€๐—ผ๐—ผ๐—ป ๐—ฎ๐˜ ๐—ฎ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ ๐˜‡๐—ผ๐—ป๐—ฒ๐˜€โ€ Congrats to all authors!!

www.biorxiv.org/content/10.1...

#MINFLUX #DNAPAINT #MassivePhotonics #Microscopy #Bassoon

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Start revealing cellular structures with nanoscale precision today!

#SMLM #Microscopy #DNAPAINT #MassivePhotonics

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๐Ÿšจ ๐—ก๐—ฒ๐˜„ ๐——๐—ก๐—”-๐—ฃ๐—”๐—œ๐—ก๐—ง ๐—ž๐—ถ๐˜ ๐——๐—ฟ๐—ผ๐—ฝ! ๐Ÿšจ
Ready to image ๐—›๐˜‚๐—บ๐—ฎ๐—ป ๐—œ๐—ด๐—š๐˜€ at the nanoscale?
๐Ÿ”—Click here: bit.ly/3GOvpUu
Compatible with all our DNA-PAINT kits for seamless multiplexing.

#DNAPAINT #SMLM #Microscopy #MassivePhotonics

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๐Ÿ”ฌ ๐—•๐—ฒ๐—ต๐—ถ๐—ป๐—ฑ ๐˜๐—ต๐—ฒ ๐—•๐—ถ๐—ป๐—ฑ๐—ฒ๐—ฟ๐˜€: ๐— ๐—ฒ๐—ฒ๐˜ ๐—ž๐—ถ๐—บ๐—ฏ๐—ฒ๐—ฟ๐—น๐˜† ๐Ÿ”ฌ

Ever wonder what actually goes on at Massive Photonics before you get your hands on one of our ready-to-use DNA-PAINT kits?

#MassivePhotonics #SuperResolution #SMLM #CellImaging #DNAPAINT

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๐Ÿšจ New Product Alert ๐Ÿšจ
Introducing a ๐——๐—ก๐—”-๐—ฃ๐—”๐—œ๐—ก๐—ง ๐—ž๐—ถ๐˜ ๐—ณ๐—ผ๐—ฟ ๐—ฅ๐—™๐—ฃ-๐˜๐—ฎ๐—ด๐—ด๐—ฒ๐—ฑ ๐—ฃ๐—ฟ๐—ผ๐˜๐—ฒ๐—ถ๐—ป๐˜€!

๐—Ÿ๐—ฒ๐—ฎ๐—ฟ๐—ป ๐—บ๐—ผ๐—ฟ๐—ฒ: www.massive-photonics.com/product-cate...

#SMLM #DNAPAINT #Microscopy #RFP #CellImaging #MassivePhotonics

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๐Ÿ”ฌ๐—•๐—ฒ๐—ต๐—ถ๐—ป๐—ฑ ๐˜๐—ต๐—ฒ ๐—•๐—ถ๐—ป๐—ฑ๐—ฒ๐—ฟ๐˜€: ๐— ๐—ฒ๐—ฒ๐˜ ๐—ฆ๐—ฒ๐—ฏ๐—ฎ๐˜€๐˜๐—ถ๐—ฎ๐—ป๐Ÿ”ฌ
Ever wonder what actually goes on at Massive Photonics before you get your hands on one of our ready-to-use DNA-PAINT kits?

Weโ€™re shining the spotlight on Dr. Sebastian Strauss, our CTO. (1/5)

#MassivePhotonics #SuperResolution #SMLM #CellImaging

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Magenta: Tubulin, White: Vimentin, Cyan: Tom20, Blue: Lamp1, Orange: H3k9ac

Magenta: Tubulin, White: Vimentin, Cyan: Tom20, Blue: Lamp1, Orange: H3k9ac

๐—œ๐—ป๐˜๐—ฟ๐—ผ๐—ฑ๐˜‚๐—ฐ๐—ถ๐—ป๐—ด ๐—ผ๐˜‚๐—ฟ ๐—บ๐—ผ๐˜€๐˜ ๐˜ƒ๐—ฒ๐—ฟ๐˜€๐—ฎ๐˜๐—ถ๐—น๐—ฒ ๐——๐—ก๐—”-๐—ฃ๐—”๐—œ๐—ก๐—ง ๐—บ๐˜‚๐—น๐˜๐—ถ๐—ฝ๐—น๐—ฒ๐˜…๐—ถ๐—ป๐—ด ๐—ธ๐—ถ๐˜ ๐˜†๐—ฒ๐˜! MASSIVE-sdAB-FAST 1 - 6-Plex kits enable users to create a ๐—ฐ๐˜‚๐˜€๐˜๐—ผ๐—บ๐—ถ๐˜‡๐—ฒ๐—ฑ ๐—ธ๐—ถ๐˜ ๐—ณ๐—ผ๐—ฟ ๐Ÿญ โ€“ ๐Ÿฒ ๐˜๐—ฎ๐—ฟ๐—ด๐—ฒ๐˜ ๐—ถ๐—บ๐—ฎ๐—ด๐—ถ๐—ป๐—ด!

#DNAPAINT #SuperResolution #Microscopy #MassivePhotonics #PreMixing #SMLM

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๐Ÿ”ฌ ๐—•๐—ฒ๐—ต๐—ถ๐—ป๐—ฑ ๐˜๐—ต๐—ฒ ๐—•๐—ถ๐—ป๐—ฑ๐—ฒ๐—ฟ๐˜€: ๐— ๐—ฒ๐—ฒ๐˜ ๐—Ÿ๐˜‚๐—ฐ๐—ถ๐—ฎ ๐Ÿ”ฌ

Ever wonder what actually goes on at Massive Photonics before you get your hands on one of our ready-to-use DNA-PAINT kits?

#MassivePhotonics #SuperResolution #SMLM #CellImaging #FluorescenceMicroscopy #DNAPAINT

(1/4)

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๐Ÿ”ฌโ€ฏ๐๐ž๐ก๐ข๐ง๐ ๐ญ๐ก๐ž ๐๐ข๐ง๐๐ž๐ซ๐ฌ: ๐Œ๐ž๐ž๐ญ ๐€๐ง๐ ๐ž๐ฅโ€ฏ๐Ÿ”ฌ

Ever wonder whatโ€ฏactuallyโ€ฏgoes on atโ€ฏMassive Photonicsโ€ฏbefore you get your hands on one of our ready-to-use DNA-PAINT kits?

#MassivePhotonics #SuperResolutionMicroscopy #SMLM #HPLC #ProteinPurification #CellImaging #FluorescenceMicroscopy #DNAPAINT

(1/4)

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๐Ÿ”ฌ๐๐ž๐ก๐ข๐ง๐ ๐ญ๐ก๐ž ๐๐ข๐ง๐๐ž๐ซ๐ฌ: ๐Œ๐ž๐ž๐ญ ๐ˆ๐ซ๐ฒ๐ง๐š

Ever wonder what actually goes on at Massive Photonics before you get your hands on one of our ready-to-use DNA-PAINT kits?

Today weโ€™re spotlighting Iryna, our Lab Assistant.

#BehindTheBinders #MassivePhotonics #DNAPAINT #SMLM #CellImaging

(1/4)

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๐Ÿš€ Exciting news! Weโ€™re launching 6 #abberior DNA-PAINT kits optimized for #MINFLUX #microscopy!
๐Ÿ”ฌ Whatโ€™s inside? abberior.rocks/dyes-labels/...
๐ŸฉMINFLUX-optimized sequences
๐ŸŽจMINFLUX-optimized dyes
โŠฅOrthogonal sequences for up to 3-channel exchange #DNAPAINT
#Superresolution #MASSIVEPhotonics

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We also partnered with #MassivePhotonics to offer a #DNAPAINT kit that is optimized for our Nanoimager, making DNA-PAINT more accessible than ever.

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