A new concept in MRM generation — adaptive modeling of tandem MS data using spline fitting of absolute intensities.
Now in Analytical Chemistry (open access article): doi.org/10.1021/acs....
Empirical MRM transitions created for 960K compounds → METLIN 960K MRM.
#MassSpec #METLIN #AIinScience
A free version just posted—courtesy of #Nature.
Lipidomics (via #XCMS / #METLIN) reveals α-tocopherol (vitamin E) as a key player in ferroptosis resistance in cancer.
t.co/HMJSLuTAnM
#Lipidomics #CancerResearch #Ferroptosis #VitaminE
Lipidomics (& #METLIN) reveal a metabolic vulnerability in tumors @Nature doi.org/10.1038/s415...
Tumors don’t just synthesize their own lipids—they scavenge antioxidant-rich lipoproteins. @JaviGBermudez with our lab's lipidomics uncover how this can be used to impair tumor growth
Unexpected growth on the #METLIN front, now reaching 960K molecular standards with MS/MS natural product additions. 960K METLIN currently available online via XCMS-METLIN. xcmsonline.scripps.edu
@Molsystbio doi.org/10.1038/s443...
