Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation Global unbiased proteomic analysis reveals key metabolic pathways induced by Epstein-Barr virus critical for B cell growth transformation. In this issue of Cell Metabolism, Wang et al. utilized multip...

Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation #EBV #MTHFD2 #MECFS #LongCovid

www.cell.com/cell-metabol...

Binding Analysis and Structure-Based Design of Tricyclic Coumarin-Derived MTHFD2 Inhibitors as Anticancer Agents: Insights from Computational Modeling Unfolded protein response (UPR)-dependent metabolic reprogramming diverts metabolites from glycolysis to mitochondrial 1C metabolism, highlighting pharmacological resistance to folate drugs and overex...

pmc.ncbi.nlm.nih.gov/articles/PMC...

"In particular, the bifunctional mitochondrial methylenetetrahydrofolate dehydrogenase/cyclohydrolase ( #MTHFD2), that plays a key role in 1C metabolism in purine and thymidine synthesis, was identified as one of the overexpressed enzymes."

Disputation: Ke Deng - Department of Biosciences PhD candidate Ke Deng at the Department of Biosciences, Faculty of Mathematics and Natural Sciences, is defending the thesis 'Metabolic Regulation of Prostate Cancer by Endoplasmic Reticulum Stress Si...

Today: #PhD candidate Ke Deng from @biovitenskap.bsky.social is defending the thesis 'Metabolic Regulation of #Prostate #Cancer by Endoplasmic Reticulum Stress Signaling' for the degree of PhD.
Friday, Jan. 31 at 12:15 PM, Bikuben, Kristine Bonnevies hus
#MTHFD2 #MOCOS
www.mn.uio.no/ibv/english/...