I'm excited to share (what I believe to be) the first independent, free, open-source, end to end pipeline for mass photometry analysis with native support for both landing assays and SPT / dynamics. Source code, windows release, full documentation: github.com/imalreadypat...
#MassPhotometry
#Refeyn

Simulated mass photometry results showing count distributions at a constant concentration of A (150 kDa) and seven different concentrations of B (30 kDa). B free is under the limit of detection (40 kDa). A and B interact with an equilibrium dissociation constant (Kd) of 1 nM.

Screenshot of the pyPhotoMol package repository (https://github.com/osvalB/pyphotomol)

Do you want to analyze mass photometry (MP) count data with Python scripts? Try pyPhotoMol, a package to process, fit, and visualize the MP data 👨‍💻

github.com/osvalB/pypho...

pyPhotoMol is derived from PhotoMol, our web tool for MP:

spc.embl-hamburg.de/app/photoMol

#massphotometry #Python #code

#Microfluidics #MassPhotometry #SingleCellAnalysis #Nanotechnology #Biophysics #OxfordResearch #KavliOxford @oxfordchemistry.bsky.social @mplsoxford.bsky.social

#WellcomeDiscovery #MassPhotometry #Biophysics #KavliOxford @oxfordchemistry.bsky.social @ox.ac.uk @mplsoxford.bsky.social @kavlifoundation.org

@ox.ac.uk @mplsoxford.bsky.social @kavlifoundation.org @oxfordchemistry.bsky.social #MassPhotometry #Biochemistry #StructuralBiology #LifeSciences

#MeetTheResearcher

Introducing Jiri Kratochvil this week who is a postdoc in the Kukura Lab using mass photometry to study low-affinity protein-protein interactions.

#MassPhotometry #Biophysics

Monomers and short oligomers of human RAD52 promote single-strand annealing | PNAS Genome maintenance and stability rely on the repair of DNA double-strand breaks. Breaks can be repaired via the single-strand-annealing pathway med...

New paper alert! 📄
We’re thrilled to share a new publication from our lab:

"Monomers and short oligomers of human RAD52 promote single-strand annealing"

Check it out: www.pnas.org/doi/10.1073/...

#DNARepair #RAD52 #MolecularBiology #SingleMolecule #PhDResearch #MassPhotometry #StructuralBiology

Delighted to finally get this installed! New #massphotometer from #refeyn, with a shiny MassFluidix unit for low affinity interactions. Core equipment and open for all users. Fantastic team effort from many people @sheffielduni.bsky.social and funding from @ukri.org #massphotometry

@AdelaideProtein @sba_adelaide @waiteresearch @UofA_SET Adelaide Microscopy are hosting a @refeynit #massphotometry workshop with NewSpec on 23rd March. DM for details. Bring your samples for MWs, oligomerisation, complex formation. And catered lunch! Limited to 25 participants.