Structure of the 5-subunit RFC complex bound to the homotrimer DNA clamp PCNA, as determined by cryogenic electron microscopy. Courtesy of Marie Morimoto.

NIH researchers discovered Morimoto–Ryu–Malicdan syndrome, after finding shared symptoms and RFC4 gene variants in nine patients, offering hope for faster diagnosis and future treatments:
ow.ly/cmH450WGpaN.
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