Ligia Schmitd, Ph.D.’s project could reveal how Schwann cell Sonic Hedgehog signaling drives nerve repair—informing strategies to boost recovery and reduce pain after injury.
🔬 Project: Decoding Schwann Cell Sonic Hedgehog Signaling in Nerve Injury and Repair

#MerkinScholars #SchwannCells #Research

Dr. Sana Sarkar's project could uncover how miRNAs and monocarboxylate transporters drive nerve repair—guiding future therapies for peripheral neuropathy.

Project: Dissecting the role of miRNAs in monocarboxylate transporter-mediated peripheral nerve regeneration

#MerkinScholars

Dr. Jason Chua’s research could move new breakthrough treatments into clinical trials—targeting a rare form of Charcot‑Marie‑Tooth disease in children and informing therapies for many other neuropathies.

🔬 Transformative CMT4B3 Discoveries

#MerkinScholars #PatientImpact #CMT #raredisease

If successful, this project will illuminate the early biology of CMT1A, a common genetic peripheral neuropathy affecting up to 1 in 5,000 people—revealing when myelin abnormalities begin and why they occur, critical insights to enable future treatments.

#MerkinScholars #CMT

Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration - PubMed At present oral NR supplementation, at the doses used in this study, cannot be recommended to prevent neuropathy or to improve nerve regeneration.

Grateful & excited:
New paper alert by Simone Thomas with contributions from other @merkinpnnrcenter.bsky.social scholars —live on PubMed now.

pubmed.ncbi.nlm.nih.gov/41502156/

#MerkinCenter #MerkinScholars #PeripheralNeuropathy #NerveRegeneration #TeamScience #Neurology #JPNS #JohnsHopkins