Single-cell Proteomics🔥 #MarfanSyndrome
Aortic Root
Fbn1 C1041G/+🐭

2.4k proteins
3.5k cells
487 proteins/cell👈

7 Smooth Muscle Cell subtypes
Prss2, Lrp1 as modulated SMC markers

vs scRNAseq

+SeqIF (21 Ab)

#AortaEd
Sarah Parker lab #MolCellProteomics 2026
www.mcponline.org/article/S153...

Secretome of TurboID (fused with Cyp450 ER domain)-#Pericyte

2D monoculture vs 3D gliovascular spheroidal culture
Normoxia vs Hypoxia

Hypoxia-suppressed CXCL6 & OPG in 2D pericyte were not seen in 3D spheroidal pericyte

#MolCellProteomics 2024
www.sciencedirect.com/science/arti...