MBP fusion is an effective and generalizable approach to enable crystallographic studies of engineered binding proteins that are otherwise difficult to crystallize #Monobody #Aggregation #MaltoseBindingProtein doi.org/10.1107/S205...
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This review examines #GPR126's expression, #ligandreceptor interactions, signaling, and roles in development/diseases, highlighting small molecule, #peptide, and #monobody modulators as promising #aGPCRs-targeted therapies.
#OpenAccess: doi.org/10.1016/j.ge...
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