#Medsky🧪 #IDsky #immunosky #publichealth This study found that elevated markers for NETs such as #Myeloperoxidase (MPO), #NeutrophilElastase (NE) & circulating DNA were quantitatively & structurally associated with an increased size & number of microclots in #LongCOVID patients.

Cartoon view of myeloperoxidase (MPO). MPO is a homodimer, each monomer consists of a heavy and a light chain. It contains a heme cofactor.

Intriguingly, #myeloperoxidase (MPO) is a key player both for the chromatin decondensation during NETosis and it also decorates mature NETs.

It produces reactive oxygen species and is one of the most important bactericidal enzymes of neutrophils.