PepGen slumps as FDA places hold on lead drug Shares in PepGen fell sharply after the FDA placed a partial clinical hold on its lead drug for rare neuromuscular disease DM1.

#Shares in #PepGen were down more than 21% after the #FDA placed a #partialclinicalhold on its lead drug PGN-EDODM1, for rare genetic muscle disorder #myotonicdystrophytype1 (DM1).

FML i'm starting to drop weight again.

I lost 30 lbs from feb 16-the end of march.

i've lost another 5 this week...
Sept.'s appt cannot come soon enough.

#musculardystrophy #myotonicdystrophytype1 #chronicallyill #chronicillnessthings

Restoring heart function in Myotonic Dystrophy Type 1 The findings are relevant to current therapeutic approaches for DM1 that are based on increasing MBNL protein.

Dr. T Cooper, R-C Hu et al focused on #MyotonicDystrophyType1 #heart problems testing a novel approach to restore normal function. #DM1 @jclinical-invest.bsky.social @bcmhouston.bsky.social #BCMCancerCenter #BCMGradSchool #Therapy blogs.bcm.edu/2025/03/18/f...