Social stimulation promotes #NLG1 proteolysis; the resulting NLG1-CTD maintains #SocialMemory by inhibiting #cofilin to strengthen dendritic spines, offering insight into memory maintenance mechanisms. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

🚀From Bench to Paper | Unlocking the Secrets of Social Memory
Social interaction triggers #NLG1 proteolysis to generate NLG1-CTD, strengthening synapses and supporting social memory. Blocking this process impairs memory, while peptides can rescue it.
#Neuroscience #SocialMemory